cspE:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[cspE:Gene|''cspE]]'' (synonyms: ''ECK0616, b0623, JW0618, gicA, msmC'')<ref name='LIB:Riley_2006'/>
''cspE''
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!align=left {{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[cspE:Gene_Product(s)|CspE product]]<ref name='LIB:Riley_2006'/>: DNA-binding transcriptional repressor product, B0623 product, MsmC product, GicA product
''ECK0616, b0623, JW0618, gicA, msmC''<ref name='LIB:Riley_2006'/>, msmC''
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!align=left {{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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cold shock protein CspE<ref name='LIB:EcoCyc10.6'/> transcription antiterminator and regulator of RNA stability<ref name='LIB:EcoCyc11.1'/>  
cold shock protein CspE<ref name='LIB:EcoCyc10.6'/>; transcription antiterminator and regulator of RNA stability<ref name='LIB:EcoCyc11.1'/>


Binds and melts RNA, involved in cold acclimation; binds ssDNA; high copy protects the chromosome from decondensation by camphor and increases DNA supercoiling; dimeric<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Product Synonyms(s)
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''DNA-binding transcriptional repressor<ref name='LIB:Riley_2006'/>, B0623<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsmC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GicA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CspE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0616, gicA, JW0618, msmC, b0623''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:cspE|cspE]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:cspE|cspE]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=cspE&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG12179]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120002072&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=cspE&loc=MG1655%3A656515..656724,W3110%3A657714..657923,DH10B%3A595847..596056,DH10B%3A709107..709316,REL606%3A639873..640082,BW2952%3A559275..559484]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=559275&end=559484&gene=cspE&aa=mskikgnvkwfneskgfgfitpedgskdvfvhfsaiqtngfktlaegqrvefeitngakgpsaanvial]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=cspE+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=cspE]]&nbsp;&nbsp;


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Latest revision as of 21:52, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

cspE

Gene Synonym(s)

ECK0616, b0623, JW0618, gicA, msmC[1], msmC

Product Desc.

cold shock protein CspE[2]; transcription antiterminator and regulator of RNA stability[3]

Binds and melts RNA, involved in cold acclimation; binds ssDNA; high copy protects the chromosome from decondensation by camphor and increases DNA supercoiling; dimeric[4]

Product Synonyms(s)

DNA-binding transcriptional repressor[1], B0623[2][1], MsmC[2][1], GicA[2][1], CspE[2][1] , ECK0616, gicA, JW0618, msmC, b0623

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): cspE[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


The cspABEG deletion BX04 is cold-sensitive and forms filaments at 15C (Xia, 2001). CspE is a cold shock protein homolog, but is constitutively expressed at 37C. CspE has transcription antitermination activity. CspE affects rpoS and uspA expression. CspE is a negative regulator of cspA transcription. CspE binds ssDNA containing six or more contiguous dT residues with high affinity (Johnston, 2006).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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