hipA:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[hipA:Gene|''hipA]]'' (synonyms: ''ECK1500, b1507, JW1500'')<ref name='LIB:Riley_2006'/>
''hipA''
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!align=left {{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[hipA:Gene_Product(s)|HipA product]]<ref name='LIB:Riley_2006'/>: regulator with hipB product, B1507 product
''ECK1500, b1507, JW1500''<ref name='LIB:Riley_2006'/>, JW1500''
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!align=left {{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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HipA Polypeptide<ref name='LIB:EcoCyc10.6'/> serine kinase HipA<ref name='LIB:EcoCyc11.1'/>  
HipA Polypeptide<ref name='LIB:EcoCyc10.6'/>; serine kinase HipA<ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:HipB transcriptional repressor|HipB transcriptional repressor]]<ref name='LIB:EcoCyc11.1'/>
Component of [[:Category:Complex:HipB transcriptional repressor|HipB transcriptional repressor]]<ref name='LIB:EcoCyc11.1'/>


Toxin, growth inhibition blocked by continuous HipB synthesis;; probable role in cell division<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Product Synonyms(s)
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''regulator with hipB<ref name='LIB:Riley_2006'/>, B1507<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HipA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1500, JW1500, b1507''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:hipBA|hipBA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:hipBA|hipBA]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=hipA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10443]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000436&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=hipA&loc=MG1655%3A1590200..1588878,W3110%3A1593890..1592568,DH10B%3A1679825..1678503,REL606%3A1568743..1567421,BW2952%3A1480937..1482259]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1480937&end=1482259&gene=hipA&aa=mpklvtwmnnqrvgeltklangahtfkyapewlasryarplslslplqrgnitsdavfnffdnllpdspivrdrivkryhaksrqpfdllseigrdsvgavtlipedetvthpimawekltearleevltaykadiplgmireendfrisvagaqektallrigndwcipkgitptthiiklpigeirqpnatldlsqsvdneyyclllakelglnvpdaeiikagnvralaverfdrrwnaertvllrlpqedmcqtfglpssvkyesdggpgiarimaflmgssealkdrydfmkfqvfqwligatdghaknfsvfiqaggsyrltpfydiisafpvlggtgihisdlklamglnaskgkktaidkiyprhflatakvlrfpevqmheilsdfarmipaaldnvktslptdfpenvvtavesnvlrlhgrlsreygsk]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hipA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=hipA]]&nbsp;&nbsp;


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HipA serine protein kinase autophosphorylates Ser150 and this activity is essential for persister formation (Correia, 2006). HipA binds and phosphorylates TufA/TufB (Schumacher, 2009).<ref name='LIB:EcoGene'/>
HipA serine protein kinase autophosphorylates Ser150 and this activity is essential for persister formation (Correia, 2006). HipA binds and phosphorylates TufA/TufB (Schumacher, 2009).<ref name='LIB:EcoGene'/>






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==References==
==References==
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Latest revision as of 21:49, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

hipA

Gene Synonym(s)

ECK1500, b1507, JW1500[1], JW1500

Product Desc.

HipA Polypeptide[2]; serine kinase HipA[3];

Component of HipB transcriptional repressor[3]

Toxin, growth inhibition blocked by continuous HipB synthesis;; probable role in cell division[4]

Product Synonyms(s)

regulator with hipB[1], B1507[2][1], HipA[2][1] , ECK1500, JW1500, b1507

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hipBA[2]

Regulation/Activity
Quick Links



        

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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HipA serine protein kinase autophosphorylates Ser150 and this activity is essential for persister formation (Correia, 2006). HipA binds and phosphorylates TufA/TufB (Schumacher, 2009).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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