nrdA:Quickview: Difference between revisions
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{| | {| id="B49aeee45cd0bc" class=" tableEdit New_Quickview_Table" | ||
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!align=left {{table_heading_style}} | | !align=left {{table_heading_style}} |Standard Name | ||
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''nrdA'' | |||
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!align=left {{table_heading_style}} | | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK2226, b2234, JW2228, dnaF''<ref name='LIB:Riley_2006'/>, dnaF'' | |||
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!align=left {{table_heading_style}} | | !align=left {{table_heading_style}} |Product Desc. | ||
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NrdA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | NrdA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ||
Component of [[:Category:Complex:B1 protein|B1 protein]]<ref name='LIB:EcoCyc10.6'/> | Component of [[:Category:Complex:B1 protein|B1 protein]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; [[:Category:Complex:ribonucleotide reductase I|ribonucleotide reductase I]]<ref name='LIB:EcoCyc10.6'/> | ||
Ribonucleoside diphosphate reductase, subunit alpha; class I, aerobic; ribonucleotide reductase; B1 protein, R1 subunit<ref name='LIB:EcoGene'/> | |||
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!align=left {{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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''ribonucleoside diphosphate reductase 1, alpha subunit<ref name='LIB:Riley_2006'/>, B2234<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DnaF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NrdA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , dnaF, ECK2226, JW2228, b2234'' | |||
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!align=left {{table_heading_style}} |Function from GO | |||
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<GO_nr /> | |||
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!align=left {{table_heading_style}} |Knock-Out Phenotype | |||
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!align=left {{table_heading_style}} |Regulation/Expression | !align=left {{table_heading_style}} |Regulation/Expression | ||
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transcription unit(s): [[:Category:Txn_unit:nrdAB|nrdAB]]<ref name='LIB:EcoCyc10.6'/>, OP00063, nrd, nrdA | transcription unit(s): [[:Category:Txn_unit:nrdAB|nrdAB]]<ref name='LIB:EcoCyc10.6'/>, OP00063, nrd, nrdA | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=nrdA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10660]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000653&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=nrdA&loc=MG1655%3A2342887..2345172,W3110%3A2349535..2351820,DH10B%3A2433875..2436160,REL606%3A2291565..2293850,BW2952%3A2228692..2230977]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2228692&end=2230977&gene=nrdA&aa=mnqnllvtkrdgsterinldkihrvldwaaeglhnvsisqvelrshiqfydgiktsdihetiikaaadlisrdapdyqylaarlaifhlrkkaygqfeppalydhvvkmvemgkydnhlledyteeefkqmdtfidhdrdmtfsyaavkqlegkylvqnrvtgeiyesaqflyilvaaclfsnypretrlqyvkrfydavstfkislptpimsgvrtptrqfsscvliecgdsldsinatssaivkyvsqragiginagriralgspirggeafhtgcipfykhfqtavkscsqggvrggaatlfypmwhlevesllvlknnrgvegnrvrhmdygvqinklmytrllkgeditlfspsdvpglydaffadqeeferlytkyekddsirkqrvkavelfslmmqerastgriyiqnvdhcnthspfdpaiapvrqsnlcleialptkplndvndengeialctlsafnlgainnldeleelailavraldalldyqdypipaakrgamgrrtlgigvinfayylakhgkrysdgsannlthktfeaiqyyllkasnelakeqgacpwfnettyakgilpidtykkdldtianeplhydwealresikthglrnstlsalmpsetssqisnatngiepprgyvsikaskdgilrqvvpdyehlhdayellwempgndgylqlvgimqkfidqsisantnydpsrfpsgkvpmqqllkdlltaykfgvktlyyqntrdgaedaqddlvpsiqddgcesgacki]] [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=nrdA+AND+escherichia+coli]] [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=nrdA]] | |||
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{{Quickview_table_help}} | {{Quickview_table_help}} | ||
<protect><!--Quickview_notes--></protect> | <protect><!--Quickview_notes--></protect> | ||
===Notes=== | ===Notes=== | ||
{{BacktoTop}} | {{BacktoTop}} | ||
Reducing equivalents provided by glutaredoxin or thioredoxin. Binds TrxA (Kumar, 2004). About half of the overproduced protein has the first one or two amino acids removed. E. coli B native protein is reported to start with Gln. a second native E. coli B protein start may correspond to a cleavage after Leu26. Leu26 CTG codon is unlikely to be an alternative start codon in K-12 or B and no evidence of this cleavage or an alternative start codon was seen with the overproduced K-12 protein. An M-N or MN-Q cleavage by MAP would be unusual. The variable N-termini may be created by an unknown protease.<ref name='LIB:EcoGene'/> | |||
Latest revision as of 21:47, 27 May 2013
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
nrdA |
|---|---|
| Gene Synonym(s) |
ECK2226, b2234, JW2228, dnaF[1], dnaF |
| Product Desc. |
Component of B1 protein[2][3]; ribonucleotide reductase I[2] Ribonucleoside diphosphate reductase, subunit alpha; class I, aerobic; ribonucleotide reductase; B1 protein, R1 subunit[4] |
| Product Synonyms(s) |
ribonucleoside diphosphate reductase 1, alpha subunit[1], B2234[2][1], DnaF[2][1], NrdA[2][1] , dnaF, ECK2226, JW2228, b2234 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Reducing equivalents provided by glutaredoxin or thioredoxin. Binds TrxA (Kumar, 2004). About half of the overproduced protein has the first one or two amino acids removed. E. coli B native protein is reported to start with Gln. a second native E. coli B protein start may correspond to a cleavage after Leu26. Leu26 CTG codon is unlikely to be an alternative start codon in K-12 or B and no evidence of this cleavage or an alternative start codon was seen with the overproduced K-12 protein. An M-N or MN-Q cleavage by MAP would be unusual. The variable N-termini may be created by an unknown protease.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.


