dinB:Quickview: Difference between revisions

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{|   id="V49aee3c699249"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[dinB:Gene|''dinB]]'' (synonyms: ''ECK0232, b0231, JW0221, dinP'')<ref name='LIB:Riley_2006'/>
''dinB''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[dinB:Gene_Product(s)|DinB product]]<ref name='LIB:Riley_2006'/>: DNA polymerase IV product, B0231 product, DinP product
''ECK0232, b0231, JW0221, dinP''<ref name='LIB:Riley_2006'/>, dinP''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''DNA polymerase IV<ref name='LIB:Riley_2006'/>, B0231<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , dinP, ECK0232, JW0221, b0231''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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Sensitivity to 4-NQO <ref name=PMID:16407906/>
Sensitivity to 4-NQO <ref name=PMID:16407906/>
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:dinB|dinB]]<ref name='LIB:EcoCyc10.6'/> [[:Category:Txn_unit:dinB|dinB yafNOP]]<ref name=PMID:11333217/>  
transcription unit(s): [[:Category:Txn_unit:dinB|dinB]]<ref name='LIB:EcoCyc10.6'/> [[:Category:Txn_unit:dinB|dinB yafNOP]]<ref name=PMID:11333217/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=dinB&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G6115]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120002735&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=dinB&loc=MG1655%3A250898..251953,W3110%3A250898..251953,DH10B%3A225002..226057,REL606%3A255461..256516,BW2952%3A250897..251952]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=250897&end=251952&gene=dinB&aa=mrkiihvdmdcffaavemrdnpalrdipiaiggsrerrgvistanyparkfgvrsamptgmalklcphltllpgrfdaykeasnhireifsrytsrieplsldeayldvtdsvhchgsatliaqeirqtifnelqltasagvapvkflakiasdmnkpngqfvitpaevpaflqtlplakipgvgkvsaakleamglrtcgdvqkcdlvmllkrfgkfgrilwersqgiderdvnserlrksvgvertmaedihhwseceaiierlypelerrlakvkpdlliarqgvklkfddfqqttqehvwprlnkadliatarktwderrggrgvrlvglhvtlldpqmerqlvlgl]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=dinB+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=dinB]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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Part of dinB-yafNOP operon. LexA regulon. The phenotype of some dinB alleles to reduce spontaneous mutations may be due to polarity effects.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:51, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

dinB

Gene Synonym(s)

ECK0232, b0231, JW0221, dinP[1], dinP

Product Desc.

DNA polymerase IV (Y-family DNA polymerase; translesion DNA synthesis)[2][3]

DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity[4]

Product Synonyms(s)

DNA polymerase IV[1], B0231[2][1], DinB[2][1], DinP[2][1] , dinP, ECK0232, JW0221, b0231

Function from GO

<GO_nr />

Knock-Out Phenotype

Sensitivity to 4-NQO [5]

Regulation/Expression

transcription unit(s): dinB[2] dinB yafNOP[6]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


Part of dinB-yafNOP operon. LexA regulon. The phenotype of some dinB alleles to reduce spontaneous mutations may be due to polarity effects.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Jarosz, DF et al. (2006) A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates. Nature 439 225-8 PubMed
  6. ↑ Courcelle, J et al. (2001) Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. Genetics 158 41-64 PubMed
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