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{{Tab On|Quickview|nhaA}}{{Tab|Gene|nhaA}}{{Tab|Gene Product(s)|nhaA}}{{Tab|Expression|nhaA}}{{Tab|Evolution|nhaA}}{{Tab|On One Page|nhaA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[nhaA:Gene|''nhaA]]'' (synonyms: ''ECK0020, b0019, JW0018, ant, antA, hyc'')<ref name='LIB:Riley_2006'/>
''nhaA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[nhaA:Gene_Product(s)|NhaA product]]<ref name='LIB:Riley_2006'/>: sodium-proton antiporter<ref name='LIB:Riley_2006'/>, B0019<ref name='LIB:EcoCyc10.6'/>, Hyc<ref name='LIB:EcoCyc10.6'/>, Ant<ref name='LIB:EcoCyc10.6'/>, AntA<ref name='LIB:EcoCyc10.6'/>, NhaA<ref name='LIB:EcoCyc10.6'/>
''ECK0020, b0019, JW0018, ant, antA, hyc''<ref name='LIB:Riley_2006'/>
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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sodium/proton NhaA transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
sodium/proton NhaA transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


 
Na+/H+ antiporter 1, strongly pH-dependent; helps regulate intracellular pH and extrude lithium; nhaA_P1 activated by NhaR, repressed by H-NS and stimulated by Na(+)<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''sodium-proton antiporter<ref name='LIB:Riley_2006'/>, B0019<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hyc<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ant<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AntA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NhaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ant, antA, ECK0020, JW0018, b0019''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:nhaA|nhaA]]<ref name='LIB:EcoCyc10.6'/>, OP00281  
transcription unit(s): [[:Category:Txn_unit:nhaA|nhaA]]<ref name='LIB:EcoCyc10.6'/>, OP00281  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=nhaA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10652]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000645&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=nhaA&loc=MG1655%3A17489..18655,W3110%3A17489..18655,DH10B%3A17489..18655,REL606%3A17488..18654,BW2952%3A17489..18655]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=17489&end=18655&gene=nhaA&aa=mkhlhrffssdasggiiliiaailamimansgatsgwyhdfletpvqlrvgsleinknmllwindalmavffllvglevkrelmqgslaslrqaafpviaaiggmivpallylafnyadpitregwaipaatdiafalgvlallgsrvplalkiflmalaiiddlgaiiiialfytndlsmaslgvaavaiavlavlnlcgarrtgvyilvgvvlwtavlksgvhatlagvivgffiplkekhgrspakrlehvlhpwvaylilplfafanagvslqgvtldgltsilplgiiaglligkplgislfcwlalrlklahlpegttyqqimvvgilcgigftmsifiaslafgsvdpelinwaklgilvgsissavigyswlrvrlrpsv]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=nhaA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=nhaA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
nhaA P2 promoter is RpoS-regulated, but H-NS, Na(+)- and NhaR-independent.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:47, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

nhaA

Gene Synonym(s)

ECK0020, b0019, JW0018, ant, antA, hyc[1]

Product Desc.

sodium/proton NhaA transporter[2][3]

Na+/H+ antiporter 1, strongly pH-dependent; helps regulate intracellular pH and extrude lithium; nhaA_P1 activated by NhaR, repressed by H-NS and stimulated by Na(+)[4]

Product Synonyms(s)

sodium-proton antiporter[1], B0019[2][1], Hyc[2][1], Ant[2][1], AntA[2][1], NhaA[2][1] , ant, antA, ECK0020, JW0018, b0019

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): nhaA[2], OP00281

Regulation/Activity
Quick Links



        

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Notes

[back to top]


nhaA P2 promoter is RpoS-regulated, but H-NS, Na(+)- and NhaR-independent.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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