fabF:Gene Product(s): Difference between revisions

From EcoliWiki
Jump to navigation Jump to search
imported>WikiEntryBot
Automated import of articles
 
touch table
 
(102 intermediate revisions by 3 users not shown)
Line 1: Line 1:
<!--PLEASE EDIT FROM THE SECTION OR TABLE EDIT LINKS...IF YOU SEE THIS MESSAGE, YOU'RE PROBABLY IN THE WRONG PLACE-->
<!--
***************************************************************************************************************************************************
*
*
*              PLEASE EDIT FROM THE SECTION OR TABLE EDIT LINKS...IF YOU SEE THIS MESSAGE,
*                            YOU'RE PROBABLY IN THE WRONG PLACE
*
*
***************************************************************************************************************************************************
-->{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
<noinclude>{{TabsTop}}
{{Tab|Quickview|fabF}}{{Tab|Gene|fabF}}{{Tab On|Gene Product(s)|fabF}}{{Tab|Expression|fabF}}{{Tab|Evolution|fabF}}{{Tab|On One Page|fabF}}{{TabsBottom}}
{{Tab|Quickview|fabF}}{{Tab|Gene|fabF}}{{Tab On|Gene Product(s)|fabF}}{{Tab|Expression|fabF}}{{Tab|Evolution|fabF}}{{Tab|On One Page|fabF}}{{TabsBottom}}
Line 9: Line 18:
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Gene Product Resources|Resources]]
Line 18: Line 28:
</noinclude>
</noinclude>
==Nomenclature==
==Nomenclature==
<!--box uid=421aa90e079fa326b6494f812ad13e79..G469fd381b693b-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.I46aa566e2a06e-->
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. *** -->
<!--
{|{{Prettytable}}
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_nomenclature_help}}
{|  id="I46aa566e2a06e"  class=" tableEdit Product_nomenclature_table" 
 
|-
|-
!{{table heading style}} |Standard name
!align=left {{table heading style}} |Standard name
|
||
FabF product
FabF  
|-
|-
!{{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
|
||
3-oxoacyl-[acyl-carrier-protein] synthase II<ref name='LIB:Riley_2006'/>, B1095<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Vtr<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cvc<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, VtrB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FabJ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FabF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''3-oxoacyl-[acyl-carrier-protein] synthase II<ref name='LIB:Riley_2006'/>, B1095<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Vtr<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cvc<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, VtrB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FabJ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FabF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , cvc, ECK1081, fabJ, JW1081, vtr, b1095''
|-
|-
!{{table heading style}} |Product description
!align=left {{table heading style}} |Product description
|
||
FabF<ref name='LIB:EcoCyc10.6'/>; FabF<ref name='LIB:EcoCyc11.1'/>; Component of [[:Category:Complex:3-oxoacyl-ACP synthase II|3-oxoacyl-ACP synthase II]]<ref name='LIB:EcoCyc10.6'/>
FabF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
 
Component of [[:Category:Complex:3-oxoacyl-ACP synthase II|3-oxoacyl-ACP synthase II]]<ref name='LIB:EcoCyc10.6'/>


beta-Ketoacyl-ACP synthase II; KAS II; homodimeric<ref name='LIB:EcoGene'/>
|-
|-
!{{table heading style}} |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
|
||
*[http://www.brenda.uni-koeln.de/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41]<ref name='LIB:Riley_2006'/>
|-
 
|colspan='2'|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..G469fd381b693b&page=&pagename={{FULLPAGENAMEE}} edit table]
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.I46aa566e2a06e&page=22094&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table]</span> ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79..G469fd381b693b-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.I46aa566e2a06e-->
{{Product_nomenclature_help}}
 
<protect><!--Nomenclature_notes--></protect>
<protect><!--Nomenclature_notes--></protect>
===Notes===
===Notes===
Line 48: Line 68:


==Function==
==Function==
{{BacktoTop}}
<protect>
<protect>
===Gene Ontology===
<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.22094.S46aa566f91170-->
<!--box uid=421aa90e079fa326b6494f812ad13e79..K469fd382be0cc-->
<!--
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. *** -->
******************************************************************************************
{|class = 'sortable' {{Prettytable}} id='39376'
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="S46aa566f91170"  class=" tableEdit GO_table_product dataTable" 
|- {{table_heading_style}}
|- {{table_heading_style}}
!Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|-
|
 
|
GO:0003824
|
catalytic activity
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000794
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0003824
|
catalytic activity
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016038
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0003824
|
catalytic activity
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016039
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0005829
|
cytosol
|
PMID:16858726
|
IDA: Inferred from Direct Assay
|
 
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0006633
|
fatty acid biosynthetic process
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR017568
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0006633
|
fatty acid biosynthetic process
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0275
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0008152
|
metabolic process
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016038
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0008152
|
metabolic process
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016039
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0008415
|
acyltransferase activity
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0012
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0008610
|
lipid biosynthetic process
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0444
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0009058
|
biosynthetic process
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000794
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0016740
|
transferase activity
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-  
|
|
 
|
|
GO:0005737
GO:0016747
|
|
cytoplasm
transferase activity, transferring acyl groups other than amino-acyl groups
|
|
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR017568
|
|
C
F
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
required fields missing 
complete
|-
|-  
|
|
 
|
|
GO:0006654
GO:0033817
|
|
phosphatidic acid biosynthetic process
beta-ketoacyl-acyl-carrier-protein synthase II activity
|
|
GOA:spec<br />GO_REF:0000003
|
|
IEA: Inferred from Electronic Annotation
|
|
EC:2.3.1.179
|
|
P
F
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
required fields missing 
complete
|-class='sortbottom'
 
|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..K469fd382be0cc&page=&pagename={{FULLPAGENAMEE}} edit table] || || || || || || || ||
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.S46aa566f91170&page=22094&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</span> || || || || || || || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79..K469fd382be0cc-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.S46aa566f91170-->
{{Product_GO_help}}
 
===Interactions===
<span id="Interactions"></span><big>'''Interactions'''</big>
<!--box uid=421aa90e079fa326b6494f812ad13e79..T469fd385ec9e2-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.S46aa56785578a-->
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. *** -->
<!--
{|class = 'sortable' {{Prettytable}} id='39377'
******************************************************************************************
*
*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="S46aa56785578a"  class=" tableEdit Product_interactions_table dataTable" 
|- {{table heading style}}
|- {{table heading style}}
!Partner Type!!Partner!!Notes
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|-  
|
|
Protein
Protein
Line 110: Line 369:
Subunits of [[:Category:Complex:3-oxoacyl-ACP synthase II|3-oxoacyl-ACP synthase II]]  
Subunits of [[:Category:Complex:3-oxoacyl-ACP synthase II|3-oxoacyl-ACP synthase II]]  
|
|
could be indirect   
could be indirect  
|-class='sortbottom'
|
|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..T469fd385ec9e2&page=&pagename={{FULLPAGENAMEE}} edit table] || ||
 
|
   
|-
|
Protein
|
dnaK<br />
|
 
|
PMID:15690043
|
Experiment(s):EBI-887268, EBI-893240<br />
|-
|
Protein
|
dcd<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1138841<br />
|-
|
Protein
|
napG<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1138841<br />
|-
|
Protein
|
ycbZ
|
 
|
PMID:19402753
|
MALDI(Z-score):28.281884
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.S46aa56785578a&page=22094&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79..T469fd385ec9e2-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.S46aa56785578a-->
{{Product_interactions_help}}
 
<!--Function_notes--></protect>
<!--Function_notes--></protect>
===Notes===
===Notes===


==Localization==
==Localization==
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.J46a7e94851d5e-->
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="J46a7e94851d5e"  class=" tableEdit Product_localization_table" 
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.J46a7e94851d5e&page=22094&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.J46a7e94851d5e-->


<protect><!--Localization_notes--></protect>
<protect><!--Localization_notes--></protect>
===Notes===
===Notes===


==Structure and Physical Properties==
==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<protect>
===Physical Properties===
<span id="Sequence"></span><big>'''Physical Properties'''</big>
<!--box uid=421aa90e079fa326b6494f812ad13e79..A469fd3874b45a-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.N46aa567a78e15-->
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. *** -->
<!--
{|{{Prettytable}}
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_physical_properties_help}}
{|  id="N46aa567a78e15"  class=" tableEdit Product_phys_prop_table" 
 
|-
|-
!{{table heading style}} |Sequence
!align=left {{table heading style}} |Name
|
||
 
|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=3-OXOACYL-ACP-SYNTHII-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=3-OXOACYL-ACP-SYNTHII-MONOMER at EcoCyc]  
<pre>MSKRRVVVTG LGMLSPVGNT VESTWKALLA GQSGISLIDH FDTSAYATKF AGLVKDFNCE
<pre>MSKRRVVVTG LGMLSPVGNT VESTWKALLA GQSGISLIDH FDTSAYATKF AGLVKDFNCE
Line 142: Line 479:
QAVPPTINLD NPDEGCDLDF VPHEARQVSG MEYTLCNSFG FGGTNGSLIF KKI</pre>  
QAVPPTINLD NPDEGCDLDF VPHEARQVSG MEYTLCNSFG FGGTNGSLIF KKI</pre>  
|-
|-
!{{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Length
|
||
43.05 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
413
|-
|-
!{{table heading style}} |pI
!align=left {{table heading style}} |Mol. Wt
|
||
43.046 kDa
|-
|-
!{{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |pI
|
||
25900 - 26400 (calc based on 10 Y, 2 W, and 4 C residues)  
6.0 (calculated)
|-
|-
|colspan='2'|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..A469fd3874b45a&page=&pagename={{FULLPAGENAMEE}} edit table]
!align=left {{table heading style}} |Extinction coefficient
||
25,900 - 26,400 (calc based on 10 Y, 2 W, and 4 C residues)
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.N46aa567a78e15&page=22094&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79..A469fd3874b45a-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.N46aa567a78e15-->
{{Product_physical_properties_help}}
 
===Domains/Motifs/Modification Sites===
 
<!--box uid=421aa90e079fa326b6494f812ad13e79..H469fd387648e3-->
<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table>
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. *** -->
<tr align="left" valign="top">
{|class = 'sortable' {{Prettytable}} id='39379'
<td><!--box uid=421aa90e079fa326b6494f812ad13e79.22094.J46aa567ad5669-->
<!--
******************************************************************************************
*
*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="J46aa567ad5669"  class=" tableEdit Product_motif_table dataTable" 
|- {{table heading style}}
|- {{table heading style}}
!Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
|-class='sortbottom'
|-  
|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..H469fd387648e3&page=&pagename={{FULLPAGENAMEE}} edit table] || || ||
|
|}
Initiator Methionine
<!--box uid=421aa90e079fa326b6494f812ad13e79..H469fd387648e3-->
|
{{Product_domains_motifs_help}}
1
===Structure===
|
<!--box uid=421aa90e079fa326b6494f812ad13e79..K469fd3877b4e7-->
Removed
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY. Use the edit table link under the table. ***  -->
|
{|class = 'sortable' {{Prettytable}} id='39380'
[http://www.uniprot.org/uniprot/P0AAI5#section_features UniProt:P0AAI5]
|- {{table heading style}}
!Structure Type!!Organism!!Accession!!Residues covered!!Notes
|-
|
|
X-RAY DIFFRACTION
   
   
|-
|
Domain
|
3..247
|
[http://pfam.janelia.org/family/PF00109 PF00109  Beta-ketoacyl synthase, N-terminal domain]
|
|
PMID:19920124
|-
|
Domain
|
255..370
|
|
Escherichia coli
[http://pfam.janelia.org/family/PF02801 PF02801 Beta-ketoacyl synthase, C-terminal domain]
   
|
|
[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KAS 1KAS] BETA-KETOACYL-ACP SYNTHASE II FROM ESCHERICHIA COLI
 
|
|
PMID:19920124
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.J46aa567ad5669&page=22094&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.J46aa567ad5669--></td>
<td>
<!-- motifs column 2-->
   
   
|
<motif_map/>
 
</td>
|-class='sortbottom'
</tr>
|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..K469fd3877b4e7&page=&pagename={{FULLPAGENAMEE}} edit table] || || || ||
</table>
 
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.J46aa567b2dc3d-->
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_structure_help}}
{|   id="J46aa567b2dc3d"  class=" tableEdit Product_structure_table" 
 
|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=fabF
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0AAI5 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0AAI5 PSI-PRED (P0AAI5)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0AAI5 Genomes TO Protein (P0AAI5)] (GTOP)
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.J46aa567b2dc3d&page=22094&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79..K469fd3877b4e7-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.J46aa567b2dc3d-->
{{Product_structure_help}}
 
<!--Structure_notes--></protect>
</td><td></protect>
==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
<protect><!--          ***** PLEASE DO NOT EDIT BELOW THIS LINE *****        -->
</td><tr><table><!--Structure_notes--></protect>
===Notes===
===Notes===




==Gene Product Resources==
==Gene Product Resources==
<!--box uid=421aa90e079fa326b6494f812ad13e79..R469fd387a16af-->
{{BacktoTop}}
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. *** -->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.U46aa567be5845-->
{|class = 'sortable' {{Prettytable}} id='39381'
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="U46aa567be5845"  class=" tableEdit Product_resource_table" 
|- {{table_heading_style}}
|- {{table_heading_style}}
!Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference
|-class='sortbottom'
 
|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..R469fd387a16af&page=&pagename={{FULLPAGENAMEE}} edit table] || ||
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.U46aa567be5845&page=22094&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79..R469fd387a16af-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.U46aa567be5845-->
{{Product_resources_help}}
 
<protect><!--Resources_notes--></protect>
<protect><!--Resources_notes--></protect>
===Notes===
===Notes===


==Accessions in Other Databases==
==Accessions in Other Databases==
<!--box uid=421aa90e079fa326b6494f812ad13e79..V469fd387b71af-->
{{BacktoTop}}
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. *** -->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.F46aa567c3ea14-->
{|class = 'sortable' {{Prettytable}} id='39382'
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="F46aa567c3ea14"  class=" tableEdit Gene_accessions_table" 
|- {{table_heading_style}}
|- {{table_heading_style}}
!Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16129058 GI:16129058]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_415613.1 GeneID:946665]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0003705
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0AAI5 UniProtKB/Swiss-Prot:P0AAI5]
|
Escherichia coli str. K-12 substr. MG1655
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
[[EcoCyc]]
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=3-OXOACYL-ACP-SYNTHII-MONOMER EcoCyc:3-OXOACYL-ACP-SYNTHII-MONOMER] 
EcoCyc:EG12606
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|-  
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[EcoGene]]
|
|
[http://www.expasy.ch/cgi-bin/sprot-search-ac?P0AAI5 UniProt:P0AAI5] 
EcoGene:EG12606
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|-  
|
|
[http://www.sanger.ac.uk/Software/Pfam/ PFAM] ([[PFAM|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
|
[http://www.sanger.ac.uk/cgi-bin/Pfam/getacc?PF00109 PFAM:PF00109]
[http://www.ncbi.nlm.nih.gov/gene?term=946665 GeneID:946665]
|
|
Escherichia coli str. K-12 substr. MG1655
|-
|-  
|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[RegulonDB]]
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415613 RefSeq:NP_415613] 
RegulonDB:ECK120002329
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|-  
|
|
[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]])
[[EchoBASE]]
|
|
[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KAS PDB:1KAS] 
EchoBASE:EB2490
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-class='sortbottom'
 
|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..V469fd387b71af&page=&pagename={{FULLPAGENAMEE}} edit table] || ||
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.F46aa567c3ea14&page=22094&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table]</span> || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79..V469fd387b71af-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.F46aa567c3ea14-->
{{Product_accessions_help}}
 
<protect><!--Accessions_notes--></protect>
<protect><!--Accessions_notes--></protect>
===Notes===
===Notes===
Line 262: Line 723:


==Links==
==Links==
{{BacktoTop}}
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.Y46a7e94e39b04-->
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="Y46a7e94e39b04"  class=" tableEdit Links_table" 
|- {{table_heading_style}}
!|Name!!URL!!Comments
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22094.Y46a7e94e39b04&page=22094&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table]</span> || ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.22094.Y46a7e94e39b04-->


<noinclude>
<noinclude>
==References==
==References==
{{BacktoTop}}
{{RefHelp}}
{{RefHelp}}
<references/>
<references />
__NOTOC__
__NOTOC__
[[Category:GO:0005737]][[Category:GO:0006654]][[Category:Complex:3-oxoacyl-ACP synthase II]]</noinclude>
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Latest revision as of 20:34, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FabF

Synonyms

3-oxoacyl-[acyl-carrier-protein] synthase II[1], B1095[2][1], Vtr[2][1], Cvc[2][1], VtrB[2][1], FabJ[2][1], FabF[2][1] , cvc, ECK1081, fabJ, JW1081, vtr, b1095

Product description

FabF[2][3];

Component of 3-oxoacyl-ACP synthase II[2]

beta-Ketoacyl-ACP synthase II; KAS II; homodimeric[4]

EC number (for enzymes)
edit table


Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000794

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016038

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016039

F

Seeded from EcoCyc (v14.0)

complete

GO:0005829

cytosol

PMID:16858726[5]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0006633

fatty acid biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017568

P

Seeded from EcoCyc (v14.0)

complete

GO:0006633

fatty acid biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0275

P

Seeded from EcoCyc (v14.0)

complete

GO:0008152

metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016038

P

Seeded from EcoCyc (v14.0)

complete

GO:0008152

metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016039

P

Seeded from EcoCyc (v14.0)

complete

GO:0008415

acyltransferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0012

F

Seeded from EcoCyc (v14.0)

complete

GO:0008610

lipid biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0444

P

Seeded from EcoCyc (v14.0)

complete

GO:0009058

biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000794

P

Seeded from EcoCyc (v14.0)

complete

GO:0016740

transferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc (v14.0)

complete

GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017568

F

Seeded from EcoCyc (v14.0)

complete

GO:0033817

beta-ketoacyl-acyl-carrier-protein synthase II activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.3.1.179

F

Seeded from EcoCyc (v14.0)

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of 3-oxoacyl-ACP synthase II

could be indirect

Protein

dnaK

PMID:15690043[6]

Experiment(s):EBI-887268, EBI-893240

Protein

dcd

PMID:16606699[7]

Experiment(s):EBI-1138841

Protein

napG

PMID:16606699[7]

Experiment(s):EBI-1138841

Protein

ycbZ

PMID:19402753[8]

MALDI(Z-score):28.281884

edit table


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table


Notes

Structure and Physical Properties

[back to top]


Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MSKRRVVVTG LGMLSPVGNT VESTWKALLA GQSGISLIDH FDTSAYATKF AGLVKDFNCE
DIISRKEQRK MDAFIQYGIV AGVQAMQDSG LEITEENATR IGAAIGSGIG GLGLIEENHT
SLMNGGPRKI SPFFVPSTIV NMVAGHLTIM YGLRGPSISI ATACTSGVHN IGHAARIIAY
GDADVMVAGG AEKASTPLGV GGFGAARALS TRNDNPQAAS RPWDKERDGF VLGDGAGMLV
LEEYEHAKKR GAKIYAELVG FGMSSDAYHM TSPPENGAGA ALAMANALRD AGIEASQIGY
VNAHGTSTPA GDKAEAQAVK TIFGEAASRV LVSSTKSMTG HLLGAAGAVE SIYSILALRD
QAVPPTINLD NPDEGCDLDF VPHEARQVSG MEYTLCNSFG FGGTNGSLIF KKI
Length

413

Mol. Wt

43.046 kDa

pI

6.0 (calculated)

Extinction coefficient

25,900 - 26,400 (calc based on 10 Y, 2 W, and 4 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P0AAI5

Domain

3..247

PF00109 Beta-ketoacyl synthase, N-terminal domain

PMID:19920124[9]

Domain

255..370

PF02801 Beta-ketoacyl synthase, C-terminal domain

PMID:19920124[9]

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fabF taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table


Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129058

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946665

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003705

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AAI5

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12606

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12606

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946665

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002329

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2490

Escherichia coli str. K-12 substr. MG1655

edit table


Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  6. ↑ Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  7. ↑ 7.0 7.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  9. ↑ 9.0 9.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=fabF:Gene_Product(s)&oldid=1493061"