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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[yicO:Gene|''yicO]]'' (synonyms: ''ECK3655, b3664, JW5636'')<ref name='LIB:Riley_2006'/>
''yicO''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[yicO:Gene_Product(s)|YicO product]]<ref name='LIB:Riley_2006'/>: predicted xanthine/uracil permase product, B3664 product
''ECK3655, b3664, JW5636''<ref name='LIB:Riley_2006'/>, JW5636, pbuA''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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putative membrane protein with possible relationship to novobiocin and deoxycholate resistance<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
putative membrane protein with possible relationship to novobiocin and deoxycholate resistance<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Probable adenine permease<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''predicted xanthine/uracil permase<ref name='LIB:Riley_2006'/>, B3664<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YicO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3655, JW5636, pbuA, b3664''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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|-
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:yicO|yicO]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:yicO|yicO]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=yicO&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11691]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001634&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=yicO&loc=MG1655%3A3841812..3840478,W3110%3A3796626..3797960,REL606%3A3803721..3802387,DH10B%3A3939396..3938062,BW2952%3A3728811..3730145]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3728811&end=3730145&gene=yicO&aa=miiitepllsfvlqkqgiksppmdkkmnndntdyvsnesgtlsrlfklpqhgttvrteliagmttfltmvyivfvnpqilgaaqmdpkvvfvttcliagigsiamgifanlpvalapamglnaffafvvvgamgiswqtgmgaifwgavglflltlfrirywmisniplslrigitsgiglfialmglkntgvivankdtlvmigdlsshgvllgilgffiitvlssrhfhaavlvsivvtsccglffgdvhfsgvysippdisgvigevdlsgaltlelagiifsfmlinlfdssgtligvtdkaglidgngkfpnmnkalyvdsvssvagafigtssvtayiestsgvavggrtgltavvvgvmfllvmffsplvaivppyatagalifvgvlmtsslarvnwddftesvpafittvmmpftfsitegialgfmsycimkvctgrwrdlnlcvvvvaalfalkiilvd]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=yicO+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=yicO]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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Paralogs YicO and PurP are 74% identical. PurP seems to account for all the high-affinity permease activity and it is unlikley that YicO is the low affinity activity, so YicO may need to be induced by BaeSR to get activity. yicO and the adajcent adenine deaminase gene ade may constitute an inducible adenine utilization divergon, however the convergent gene arrangement is not conserved outside of E. coli: the genes are adjacent in Klebsiella and Serratia in an apparent operon arrangement; this difference may reflect horizontal acquisition of ade, which is predicted to be an HT gene although yicO is a core gene, so their association may be a relatively recent evolutionary development. BaeSR regulon.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:40, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

yicO

Gene Synonym(s)

ECK3655, b3664, JW5636[1], JW5636, pbuA

Product Desc.

putative membrane protein with possible relationship to novobiocin and deoxycholate resistance[2][3]

Probable adenine permease[4]

Product Synonyms(s)

predicted xanthine/uracil permase[1], B3664[2][1], YicO[2][1] , ECK3655, JW5636, pbuA, b3664

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yicO[2]

Regulation/Activity
Quick Links



        

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Notes

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Paralogs YicO and PurP are 74% identical. PurP seems to account for all the high-affinity permease activity and it is unlikley that YicO is the low affinity activity, so YicO may need to be induced by BaeSR to get activity. yicO and the adajcent adenine deaminase gene ade may constitute an inducible adenine utilization divergon, however the convergent gene arrangement is not conserved outside of E. coli: the genes are adjacent in Klebsiella and Serratia in an apparent operon arrangement; this difference may reflect horizontal acquisition of ade, which is predicted to be an HT gene although yicO is a core gene, so their association may be a relatively recent evolutionary development. BaeSR regulon.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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