relA:Quickview: Difference between revisions

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{|   id="E49b0221316a9d"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[relA:Gene|''relA]]'' (synonyms: ''ECK2778, b2784, JW2755, RC'')<ref name='LIB:Riley_2006'/>
''relA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[relA:Gene_Product(s)|RelA product]]<ref name='LIB:Riley_2006'/>: (p)ppGpp synthetase I/GTP pyrophosphokinase product, B2784 product, ppGpp synthase I product
''ECK2778, b2784, JW2755, RC''<ref name='LIB:Riley_2006'/>, RC''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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RELA-MONOMER<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
RELA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


ATP:GTP 3'-pyrophosphotransferase, ppGpp synthetase I; required for ppGpp synthesis during stringent response to amino acid starvation; self regulated<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''(p)ppGpp synthetase I/GTP pyrophosphokinase<ref name='LIB:Riley_2006'/>, B2784<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RelA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ppGpp synthase I<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2778, JW2755, RC, b2784''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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|-
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:relA-mazEF|relA-mazEF]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>, relA-chpRA, chpA  
transcription unit(s): [[:Category:Txn_unit:relA-mazEF|relA-mazEF]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>, relA-chpRA, chpA  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=relA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10835]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000826&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=relA&loc=MG1655%3A2911673..2909439,W3110%3A2912307..2910073,REL606%3A2802579..2800345,DH10B%3A3005551..3001981,BW2952%3A2795251..2797257,BW2952%3A2798546..2798821]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2798546&end=2798821&gene=relA&aa=mvavrsahinkagefdpekwiaslgitsqksceclaetwayclqqtqghpdaslllwrgvemveilstlsmdidtlraallfpladanvvsedvlresvgksvvnlihgvrdmaairqlkathtdsvsseqvdnvrrmllamvddfrcvviklaeriahlrevkdapedervlaakectniyaplanrlgigqlkweledycfrylhpteykriakllherrldrehyieefvghlraemkaegvkaevygrpkhiysiwrkmqkknlafdelfdvravrivaerlqdcyaalgivhthyrhlpdefddyvanpkpngyqsihtvvlgpggktveiqirtkqmhedaelgvaahwkykegaaaggarsghedriawlrkliawqeemadsgemldevrsqvfddrvyvftpkgdvvdlpagstpldfayhihsdvghrcigakiggrivpftyqlqmgdqieiitqkqpnpsrdwlnpnlgyvttsrgrskihawfrkqdrdknilagrqilddelehlgislkeaekhllprynfndvdellaaigggdirlnqmvnflqsqfnkpsaeeqdaaalkqlqqksytpqnrskdngrvvvegvgnlmhhiarccqpipgdeivgfitqgrgisvhradceqlaelrshaperivdavwgesysagyslvvrvvandrsgllrdittilanekvnvlgvasrsdtkqqlatidmtieiynlqvlgrvlgklnqvpdvidarrlhgs]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=relA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=relA]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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RelA has two physically and functionally distinct domains, the N-terminal domain, amino acids 1 to 455, is responsible for (p)ppGpp synthesis, and the C-terminal domain, amino acids  456 to 744, is responsible for self regulation.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:43, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

relA

Gene Synonym(s)

ECK2778, b2784, JW2755, RC[1], RC

Product Desc.

RELA[2][3]

ATP:GTP 3'-pyrophosphotransferase, ppGpp synthetase I; required for ppGpp synthesis during stringent response to amino acid starvation; self regulated[4]

Product Synonyms(s)

(p)ppGpp synthetase I/GTP pyrophosphokinase[1], B2784[2][1], RelA[2][1], ppGpp synthase I[2][1] , ECK2778, JW2755, RC, b2784

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): relA-mazEF[2][3], relA-chpRA, chpA

Regulation/Activity
Quick Links



        

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Notes

[back to top]


RelA has two physically and functionally distinct domains, the N-terminal domain, amino acids 1 to 455, is responsible for (p)ppGpp synthesis, and the C-terminal domain, amino acids 456 to 744, is responsible for self regulation.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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