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{{Tab On|Quickview|yjgF}}{{Tab|Gene|yjgF}}{{Tab|Gene Product(s)|yjgF}}{{Tab|Expression|yjgF}}{{Tab|Evolution|yjgF}}{{Tab|On One Page|yjgF}}{{TabsBottom}}
{{Tab On|Quickview|yjgF}}{{Tab|Gene|yjgF}}{{Tab|Gene Product(s)|yjgF}}{{Tab|Expression|yjgF}}{{Tab|Evolution|yjgF}}{{Tab|On One Page|yjgF}}{{TabsBottom}}
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{|   id="J49b033a1eda26"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[yjgF:Gene|''yjgF]]'' (synonyms: ''ECK4238, b4243, JW5755'')<ref name='LIB:Riley_2006'/>
''ridA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[yjgF:Gene_Product(s)|YjgF product]]<ref name='LIB:Riley_2006'/>: ketoacid-binding protein<ref name='LIB:Riley_2006'/>, B4243<ref name='LIB:EcoCyc10.6'/>, YjgF<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:YjgF homotrimer|YjgF homotrimer]]<ref name='LIB:EcoCyc11.1'/>
''ECK4238, b4243, JW5755''<ref name='LIB:Riley_2006'/>, JW5755'', ''yjgF''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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conserved protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
conserved protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:YjgF homotrimer|YjgF homotrimer]]<ref name='LIB:EcoCyc11.1'/>


Function unknown; Salmonella ortholog required for full IlvE activity and for the dependence of the alternative pyrimidine biosynthesis (APB) pathway of thiamine biosynthesis upon the oxidative pentose phosphate pathway; serine sensitivity; trimeric<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''ketoacid-binding protein<ref name='LIB:Riley_2006'/>, B4243<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjgF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK4238, JW5755, b4243''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:yjgF|yjgF]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:yjgF|yjgF]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=yjgF&s=search]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=yjgF&loc=MG1655%3A4468936..4468550,W3110%3A4475593..4475207,REL606%3A4454190..4453804,DH10B%3A4570744..4570358,BW2952%3A4407285..4407671]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4407285&end=4407671&gene=yjgF&aa=msqtfyrcnkgeimsktiatenapaaigpyvqgvdlgnmiitsgqipvnpktgevpadvaaqarqsldnvkaiveaaglkvgdivkttvfvkdlndfatvnatyeafftehnatfparscvevarlpkdvkieieaiavrr]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=yjgF+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=yjgF]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
YjgF, RutC, TdcF, YoaB and YjgH are paralogs and members of a highly conserved YjgF family (pfam:PF01042) with diverse mutant phenotypes and unknown molecular function; the family members form homotrimers, some binding 2-ketoglutarate or related compounds. The rat homolog PSP (perchloric acid-soluble protein) has been reported to have endoribonuclease activity, Endoribonuclease L, against ss mRNA, inhibiting translation, but this activity has not been demonstrated for other members.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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<references/>
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Latest revision as of 18:51, 16 January 2017

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

ridA

Gene Synonym(s)

ECK4238, b4243, JW5755[1], JW5755, yjgF

Product Desc.

conserved protein[2][3];

Component of YjgF homotrimer[3]

Function unknown; Salmonella ortholog required for full IlvE activity and for the dependence of the alternative pyrimidine biosynthesis (APB) pathway of thiamine biosynthesis upon the oxidative pentose phosphate pathway; serine sensitivity; trimeric[4]

Product Synonyms(s)

ketoacid-binding protein[1], B4243[2][1], YjgF[2][1] , ECK4238, JW5755, b4243

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yjgF[2]

Regulation/Activity
Quick Links



        

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See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


YjgF, RutC, TdcF, YoaB and YjgH are paralogs and members of a highly conserved YjgF family (pfam:PF01042) with diverse mutant phenotypes and unknown molecular function; the family members form homotrimers, some binding 2-ketoglutarate or related compounds. The rat homolog PSP (perchloric acid-soluble protein) has been reported to have endoribonuclease activity, Endoribonuclease L, against ss mRNA, inhibiting translation, but this activity has not been demonstrated for other members.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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