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{{Tab On|Quickview|hupA}}{{Tab|Gene|hupA}}{{Tab|Gene Product(s)|hupA}}{{Tab|Expression|hupA}}{{Tab|Evolution|hupA}}{{Tab|On One Page|hupA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[hupA:Gene|''hupA]]'' (synonyms: ''ECK3992, b4000, JW3964, G119, hydL'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''hupA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[hupA:Gene_Product(s)|HupA product]]<ref name='LIB:Riley_2006'/>: HU, DNA-binding transcriptional regulator, alpha subunit<ref name='LIB:Riley_2006'/>, B4000<ref name='LIB:EcoCyc10.6'/>, HydL<ref name='LIB:EcoCyc10.6'/>, HupA<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:HU Transcriptional dual regulator|HU Transcriptional dual regulator]]<ref name='LIB:EcoCyc11.1'/>
''ECK3992, b4000, JW3964, G119, hydL''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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DNA-binding protein HU-&alpha; (HU-2)<ref name='LIB:EcoCyc10.6'/>Transcriptional dual regulator  HU-&alpha; (HU-2)<ref name='LIB:EcoCyc11.1'/>
DNA-binding protein HU-&alpha; (HU-2)<ref name='LIB:EcoCyc10.6'/>; Transcriptional dual regulator  HU-&alpha; (HU-2)<ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:HU Transcriptional dual regulator|HU Transcriptional dual regulator]]<ref name='LIB:EcoCyc11.1'/>


Histone-like protein HU-alpha, HU-2<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''HU, DNA-binding transcriptional regulator, alpha subunit<ref name='LIB:Riley_2006'/>, B4000<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HydL<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HupA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3992, JW3964, b4000''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:hupA|hupA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:hupA|hupA]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=hupA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10466]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000459&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=hupA&loc=MG1655%3A4198304..4198576,W3110%3A3436400..3436128,DH10B%3A4298000..4298272,REL606%3A4179893..4180165,BW2952%3A4087984..4088256]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4087984&end=4088256&gene=hupA&aa=mnktqlidviaekaelsktqakaalestlaaiteslkegdavqlvgfgtfkvnhraertgrnpqtgkeikiaaanvpafvsgkalkdavk]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hupA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=hupA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
HU concentration in the cell determines the mechanical effect; flexible bends responsible for compaction occur at concentrations <100nM, while increased concentrations result in the formation of a rigid nucleoprotein filament and no significant concentration. Mutant HU alters structure and function of the chromosome. HT_Cmplx32_Mem: CspC+Hns+HupA.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:49, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

hupA

Gene Synonym(s)

ECK3992, b4000, JW3964, G119, hydL[1][2]

Product Desc.

DNA-binding protein HU-α (HU-2)[2]; Transcriptional dual regulator HU-α (HU-2)[3];

Component of HU Transcriptional dual regulator[3]

Histone-like protein HU-alpha, HU-2[4]

Product Synonyms(s)

HU, DNA-binding transcriptional regulator, alpha subunit[1], B4000[2][1], HydL[2][1], HupA[2][1] , ECK3992, JW3964, b4000

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hupA[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


HU concentration in the cell determines the mechanical effect; flexible bends responsible for compaction occur at concentrations <100nM, while increased concentrations result in the formation of a rigid nucleoprotein filament and no significant concentration. Mutant HU alters structure and function of the chromosome. HT_Cmplx32_Mem: CspC+Hns+HupA.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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