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{{Tab On|Quickview|sirA}}{{Tab|Gene|sirA}}{{Tab|Gene Product(s)|sirA}}{{Tab|Expression|sirA}}{{Tab|Evolution|sirA}}{{Tab|On One Page|sirA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[sirA:Gene|''sirA]]'' (synonyms: ''yhhP, ECK3454, b3470, JW3435, tusA'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc11.1'/><ref name='LIB:EcoCyc10.6'/>
''tusA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[sirA:Gene_Product(s)|YhhP product]]<ref name='LIB:Riley_2006'/>: conserved protein required for cell growth<ref name='LIB:Riley_2006'/>, B3470<ref name='LIB:EcoCyc10.6'/>, YhhP<ref name='LIB:EcoCyc10.6'/>, SirA<ref name='LIB:EcoCyc10.6'/>, TusA<ref name='LIB:EcoCyc10.6'/>
''yhhP, ECK3454, b3470, JW3435, tusA''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc11.1'/><ref name='LIB:EcoCyc10.6'/>, sirA, tusA''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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sulfur transfer protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
sulfur transfer protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


 
2-thiolation step of mnm(5)-s(2)U34-tRNA synthesis; motility defect; affects RpoS stability; may bind RNA; mutants form filaments dues to disruption of ftsZ ring; suppressed by multicopy ftsZ or dksA; required for cell growth<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''conserved protein required for cell growth<ref name='LIB:Riley_2006'/>, B3470<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhhP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SirA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TusA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , TusA, ECK3454, JW3435, tusA, yhhP, b3470''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:tusA|tusA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:tusA|tusA]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=tusA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG12216]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120002103&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=tusA&loc=MG1655%3A3607019..3606774,W3110%3A4031419..4031664,REL606%3A3539684..3539439,DH10B%3A3704764..3704519,BW2952%3A3495268..3495513]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3495268&end=3495513&gene=tusA&aa=mtdlfsspdhtldalglrcpepvmmvrktvrnmqpgetlliiaddpattrdipgfctfmehelvaketdglpyrylirkgg]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=tusA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=tusA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
SirA(TusA) interacts with and activates IscS, accepting sulfur from IscS to form C19 persulfide; transfers C19 persulfide to C78 of YheN(TusD). The gene name tus has already been used as a primary gene name, so tusA-E are kept as synonyms in EcoGene.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:46, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

tusA

Gene Synonym(s)

yhhP, ECK3454, b3470, JW3435, tusA[1][2][3], sirA, tusA

Product Desc.

sulfur transfer protein[3][2]

2-thiolation step of mnm(5)-s(2)U34-tRNA synthesis; motility defect; affects RpoS stability; may bind RNA; mutants form filaments dues to disruption of ftsZ ring; suppressed by multicopy ftsZ or dksA; required for cell growth[4]

Product Synonyms(s)

conserved protein required for cell growth[1], B3470[3][1], YhhP[3][1], SirA[3][1], TusA[3][1] , TusA, ECK3454, JW3435, tusA, yhhP, b3470

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): tusA[3]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


SirA(TusA) interacts with and activates IscS, accepting sulfur from IscS to form C19 persulfide; transfers C19 persulfide to C78 of YheN(TusD). The gene name tus has already been used as a primary gene name, so tusA-E are kept as synonyms in EcoGene.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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