nusG:Quickview: Difference between revisions

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*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **  
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!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''nusG''  
''nusG''
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3973, b3982, JW3945''<ref name='LIB:Riley_2006'/>
''ECK3973, b3982, JW3945''<ref name='LIB:Riley_2006'/>, JW3945''
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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transcription termination factor<ref name='LIB:Riley_2006'/>, B3982<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NusG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''transcription termination factor<ref name='LIB:Riley_2006'/>, B3982<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NusG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3973, JW3945, b3982''
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!align=left {{table_heading_style}} |Function from GO
!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Quick Links
!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=nusG&loc=MG1655:4175766..4176311,W3110:3458938..3458393,DH10B:4275462..4276007,REL606:4157354..4157899 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4157354&end=4157899&gene=nusG&aa=mseapkkrwyvvqafsgfegrvatslrehiklhnmedlfgevmvpteevveirggqrrkserkffpgyvlvqmvmndaswhlvrsvprvmgfiggtsdrpapisdkevdaimnrlqqvgdkprpktlfepgemvrvndgpfadfngvveevdyeksrlkvsvsifgratpveldfsqveka Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=nusG+AND+escherichia+coli Pubmed(nusG)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=nusG Textpresso(nusG)]
[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=nusG&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10667]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000660&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=nusG&loc=MG1655%3A4175766..4176311,W3110%3A3458938..3458393,DH10B%3A4275462..4276007,REL606%3A4157354..4157899,BW2952%3A4065446..4065991]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4065446&end=4065991&gene=nusG&aa=mseapkkrwyvvqafsgfegrvatslrehiklhnmedlfgevmvpteevveirggqrrkserkffpgyvlvqmvmndaswhlvrsvprvmgfiggtsdrpapisdkevdaimnrlqqvgdkprpktlfepgemvrvndgpfadfngvveevdyeksrlkvsvsifgratpveldfsqveka]]&nbsp;&nbsp; [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=nusG+AND+escherichia+coli]]&nbsp;&nbsp; [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=nusG]]&nbsp;&nbsp;


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Binds TrxA (Kumar, 2004).<ref name='LIB:EcoGene'/>
Binds TrxA (Kumar, 2004).<ref name='LIB:EcoGene'/>
Binds Rho <ref name='PMID:8422985'/>
Required for Rho-dependent termination in vivo <ref name='PMID:1547498'/> and enhances Rho-dependent termination in vitro <ref name='PMID:7525972'/> <ref name='PMID:7761393'/>
<ref name='PMID:8757798'/>
Maintains genomic integrity <ref name='PMID:21183718'/>
Essential in ''rac+'' strains to prevent expression of toxic prophage gene ''kilR'' <ref name='PMID:18487194'/>






<noinclude>
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==References==
==References==
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{{BacktoTop}}

Latest revision as of 21:47, 27 May 2013

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

nusG

Gene Synonym(s)

ECK3973, b3982, JW3945[1], JW3945

Product Desc.

transcription termination factor NusG[2][3]

Stabilizes phage lambda protein N-NusA-RNAP antitermination complex[4]

Product Synonyms(s)

transcription termination factor[1], B3982[2][1], NusG[2][1] , ECK3973, JW3945, b3982

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): secE-nusG[2]

Regulation/Activity
Quick Links



        

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Notes

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Binds TrxA (Kumar, 2004).[4]

Binds Rho [5]

Required for Rho-dependent termination in vivo [6] and enhances Rho-dependent termination in vitro [7] [8] [9]

Maintains genomic integrity [10]

Essential in rac+ strains to prevent expression of toxic prophage gene kilR [11]




References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Li, J et al. (1993) Elongation factor NusG interacts with termination factor rho to regulate termination and antitermination of transcription. Genes Dev. 7 161-72 PubMed
  6. ↑ Sullivan, SL & Gottesman, ME (1992) Requirement for E. coli NusG protein in factor-dependent transcription termination. Cell 68 989-94 PubMed
  7. ↑ Nehrke, KW & Platt, T (1994) A quaternary transcription termination complex. Reciprocal stabilization by Rho factor and NusG protein. J. Mol. Biol. 243 830-9 PubMed
  8. ↑ Burns, CM & Richardson, JP (1995) NusG is required to overcome a kinetic limitation to Rho function at an intragenic terminator. Proc. Natl. Acad. Sci. U.S.A. 92 4738-42 PubMed
  9. ↑ Washburn, RS et al. (1996) The mechanism of early transcription termination by Rho026. J. Mol. Biol. 260 347-58 PubMed
  10. ↑ Washburn, RS & Gottesman, ME (2011) Transcription termination maintains chromosome integrity. Proc. Natl. Acad. Sci. U.S.A. 108 792-7 PubMed
  11. ↑ Cardinale, CJ et al. (2008) Termination factor Rho and its cofactors NusA and NusG silence foreign DNA in E. coli. Science 320 935-8 PubMed
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