mobA:Gene Product(s): Difference between revisions

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|-
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!align=left {{table heading style}} |Standard name
!align=left {{table heading style}} |Standard name
||
||
MobA product
MobA  
|-
|-
!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
||
molybdopterin-guanine dinucleotide synthase product<ref name='LIB:Riley_2006'/>, B3857 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mob product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NarB product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ChlB product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MobA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, molybdopterin-guanine dinucleotide, protein Ar product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, protein FA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''molybdopterin-guanine dinucleotide synthase<ref name='LIB:Riley_2006'/>, B3857<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mob<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NarB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ChlB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MobA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, molybdopterin-guanine dinucleotide, protein Ar<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, protein FA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , chlB, ECK3849, JW3829, mob, narB, b3857''
|-
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!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
||
||
EG11829-MONOMER<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
EG11829<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Molybdopterin guanine dinucleotide synthesis; chlorate resistance<ref name='LIB:EcoGene'/>
|-
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!align=left {{table heading style}} |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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*


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<protect><!--Nomenclature_notes--></protect>
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===Notes===
===Notes===
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{{BacktoTop}}
{{BacktoTop}}
<protect>
<protect>
<big>'''Gene Ontology'''</big><br />{{Product_GO_help}}<!--box uid=421aa90e079fa326b6494f812ad13e79.28327.F46ab087f4fe91-->
<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.28327.F46ab087f4fe91-->
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
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[[Category:GO:0000166_!_nucleotide_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0000166_!_nucleotide_binding GO:0000166]
GO:0000166
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|
nucleotide binding
nucleotide binding
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|
[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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[http://www.uniprot.org/keywords/KW-0547 SP_KW:KW-0547]
SP_KW:KW-0547
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F
F
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|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
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complete  
complete  
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|
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[[Category:GO:0000287_!_magnesium_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0000287_!_magnesium_ion_binding GO:0000287]
GO:0000287
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magnesium ion binding
magnesium ion binding
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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|
[http://www.uniprot.org/keywords/KW-0460 SP_KW:KW-0460]
SP_KW:KW-0460
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F
F
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|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
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complete  
complete  
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[[Category:GO:0003824_!_catalytic_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003824_!_catalytic_activity GO:0003824]
GO:0003824
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catalytic activity
catalytic activity
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
GOA:interpro<br />GO_REF:0000002
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IEA: Inferred from Electronic Annotation
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InterPro:IPR013482
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F
|
Seeded from [[EcoCyc]] (v14.0)
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complete
|-  
|
 
|
GO:0005525
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GTP binding
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GOA:hamap<br />GO_REF:0000020
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR013482 InterPro:IPR013482]
HAMAP:MF_00316
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F
F
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|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
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complete  
complete  
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|
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[[Category:GO:0005525_!_GTP_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0005525_!_GTP_binding GO:0005525]
GO:0005525
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GTP binding
GTP binding
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|
[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000020 GO_REF:0000020]
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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[http://www.uniprot.org/keywords/KW-0342 SP_KW:KW-0342]<br />HAMAP:MF_00316
SP_KW:KW-0342
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F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0005737
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cytoplasm
|
GOA:hamap<br />GO_REF:0000020
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IEA: Inferred from Electronic Annotation
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HAMAP:MF_00316
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C
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Seeded from [[EcoCyc]] (v14.0)
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complete
|-
|
 
|
GO:0005737
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cytoplasm
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GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0963
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C
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Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0005737
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cytoplasm
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GO_REF:0000023
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IEA: Inferred from Electronic Annotation
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SP_SL:SL-0086
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C
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Seeded from [[EcoCyc]] (v14.0)
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complete
|-
|
 
|
GO:0006777
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Mo-molybdopterin cofactor biosynthetic process
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GOA:hamap<br />GO_REF:0000020
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IEA: Inferred from Electronic Annotation
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HAMAP:MF_00316
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P
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Seeded from [[EcoCyc]] (v14.0)
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complete
|-
|
 
|
GO:0006777
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Mo-molybdopterin cofactor biosynthetic process
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GOA:interpro<br />GO_REF:0000002
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IEA: Inferred from Electronic Annotation
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InterPro:IPR013482
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P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0006777
|
Mo-molybdopterin cofactor biosynthetic process
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GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0501
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P
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Seeded from [[EcoCyc]] (v14.0)
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|
complete  
complete  


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!|Partner Type!!Partner!!Notes
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
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Protein
|
rplV<br />
|
 
|
PMID:15690043
|
Experiment(s):EBI-889108<br />
|-
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Protein
|
pflA<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1146806<br />
|-
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Protein
|
rluB<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1146806<br />
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Protein
|
pstB<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1146806<br />
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Protein
|
uidR<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1146806<br />
|-
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Protein
|
fre<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1146806<br />
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Protein
|
dsbA<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1146806<br />


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<!--Function_notes--></protect>
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===Notes===
===Notes===
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!|Compartment!!Description!!Evidence!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes


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!align=left {{table heading style}} |Name
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PVVWVHDGER DHPTIALVNR AIEPLLLEYL QAGERRVMVF MRLAGGHAVD FSDHKDAFVN
PVVWVHDGER DHPTIALVNR AIEPLLLEYL QAGERRVMVF MRLAGGHAVD FSDHKDAFVN
VNTPEELARW QEKR</pre>  
VNTPEELARW QEKR</pre>  
|-
!align=left {{table heading style}} |Length
||
194
|-
|-
!align=left {{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
||
||
21.64 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
21.642 kDa
|-
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!align=left {{table heading style}} |pI
!align=left {{table heading style}} |pI
||
||
6.3 (calculated)
|-
|-
!align=left {{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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||
27960 - 28210 (calc based on 4 Y, 4 W, and 2 C residues)  
27,960 - 28,210 (calc based on 4 Y, 4 W, and 2 C residues)


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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
 
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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table>
<tr align="left" valign="top">
<td><!--box uid=421aa90e079fa326b6494f812ad13e79.28327.M46ab0885285fc-->
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!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References


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<!-- motifs column 2-->
<motif_map/>
</td>
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</table>


<span id="Structure"></span><big>'''Structure'''</big>
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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|-
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!align=left {{table heading style}} |Structures
!align=left {{table heading style}} |Structures
||
||
<beststructure>mobA
<beststructure>
562</beststructure>
gene=mobA
 
taxon=562,83333
</beststructure>
|-
|-
!align=left {{table heading style}} |Models
!align=left {{table heading style}} |Models
||
||
View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=mobA&sub=keywordSearc EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P32173 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=mobA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P32173 PSI-PRED (P32173)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P32173 Genomes TO Protein (P32173)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
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[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16131698 GI:16131698]
|
Escherichia coli str. K-12 substr. MG1655
|-
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[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_418294.1 GeneID:948349]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0012593
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
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[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
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[http://www.uniprot.org/uniprot/P32173 UniProtKB/Swiss-Prot:P32173]
|
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[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11829-MONOMER EcoCyc:EG11829-MONOMER]
Escherichia coli str. K-12 substr. MG1655
|-  
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[[EcoCyc]]
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EcoCyc:EG11829
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
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[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[EcoGene]]
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[[uniprot:P32173|UniProt:P32173]]
EcoGene:EG11829
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
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[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_418294 RefSeq:NP_418294]
[http://www.ncbi.nlm.nih.gov/gene?term=948349 GeneID:948349]
|
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Escherichia coli str. K-12 substr. MG1655
|-  
|-  
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[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
[[RegulonDB]]
|
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[http://salilab.org/modbase/searchbyid?databaseID=P32173 ModBase:P32173]
RegulonDB:ECK120001761
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
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[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]])
[[EchoBASE]]
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[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1E5K PDB:1E5K]
EchoBASE:EB1776
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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__NOTOC__
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===Categories===
===Categories===
{{BacktoTop}}
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]
[[Category:GO:0006777_!_Mo-molybdopterin cofactor biosynthetic process]][[Category:Products with structures in PDB]]

Latest revision as of 21:09, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MobA

Synonyms

molybdopterin-guanine dinucleotide synthase[1], B3857[2][1], Mob[2][1], NarB[2][1], ChlB[2][1], MobA[2][1], molybdopterin-guanine dinucleotide, protein Ar[2][1], protein FA[2][1] , chlB, ECK3849, JW3829, mob, narB, b3857

Product description

EG11829[2][3]

Molybdopterin guanine dinucleotide synthesis; chlorate resistance[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0000287

magnesium ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0460

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013482

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00316

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0342

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00316

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00316

P

Seeded from EcoCyc (v14.0)

complete

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013482

P

Seeded from EcoCyc (v14.0)

complete

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0501

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rplV

PMID:15690043[5]

Experiment(s):EBI-889108

Protein

pflA

PMID:16606699[6]

Experiment(s):EBI-1146806

Protein

rluB

PMID:16606699[6]

Experiment(s):EBI-1146806

Protein

pstB

PMID:16606699[6]

Experiment(s):EBI-1146806

Protein

uidR

PMID:16606699[6]

Experiment(s):EBI-1146806

Protein

fre

PMID:16606699[6]

Experiment(s):EBI-1146806

Protein

dsbA

PMID:16606699[6]

Experiment(s):EBI-1146806
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MNLMTTITGV VLAGGKARRM GGVDKGLLEL NGKPLWQHVA DALMTQLSHV VVNANRHQEI
YQASGLKVIE DSLADYPGPL AGMLSVMQQE AGEWFLFCPC DTPYIPPDLA ARLNHQRKDA
PVVWVHDGER DHPTIALVNR AIEPLLLEYL QAGERRVMVF MRLAGGHAVD FSDHKDAFVN
VNTPEELARW QEKR
Length

194

Mol. Wt

21.642 kDa

pI

6.3 (calculated)

Extinction coefficient

27,960 - 28,210 (calc based on 4 Y, 4 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mobA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131698

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948349

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0012593

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P32173

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11829

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11829

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948349

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001761

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1776

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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