maeB:Gene Product(s): Difference between revisions

Standard name	MaeB
Synonyms	fused malic enzyme predicted oxidoreductase^[1], predicted phosphotransacetylase^[1], B2463^[2]^[1], YpfF^[2]^[1], MaeB^[2]^[1] , ECK2458, JW2447, ypfF, b2463
Product description	MaeB^[2]^[3]; Component of malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)^[2]^[3] NADP-dependent malic enzyme; NADP-ME^[4]
EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0004473	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity	GOA:spec GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:1.1.1.40	F	Seeded from EcoCyc (v14.0)	complete
	GO:0004473	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity	PMID:11092847^[5]	IMP: Inferred from Mutant Phenotype		F	Seeded from EcoCyc (v14.0)	complete
	GO:0005829	cytosol	PMID:16858726^[6]	IDA: Inferred from Direct Assay		C	Seeded from EcoCyc (v14.0)	complete
	GO:0008152	metabolic process	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002505	P	Seeded from EcoCyc (v14.0)	complete
	GO:0008152	metabolic process	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR016040	P	Seeded from EcoCyc (v14.0)	complete
	GO:0008415	acyltransferase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002505	F	Seeded from EcoCyc (v14.0)	complete
	GO:0046872	metal ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012188	F	Seeded from EcoCyc (v14.0)	complete
	GO:0046872	metal ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015884	F	Seeded from EcoCyc (v14.0)	complete
	GO:0046872	metal ion binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F	Seeded from EcoCyc (v14.0)	complete
	GO:0051287	NAD or NADH binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012302	F	Seeded from EcoCyc (v14.0)	complete
	GO:0055114	oxidation reduction	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012188	P	Seeded from EcoCyc (v14.0)	complete
	GO:0055114	oxidation reduction	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015884	P	Seeded from EcoCyc (v14.0)	complete
	GO:0055114	oxidation reduction	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0560	P	Seeded from EcoCyc (v14.0)	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
Protein	Subunits of malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)	could be indirect
Protein	cca		PMID:15690043^[7]	Experiment(s):EBI-881656
Protein	hrpA		PMID:15690043^[7]	Experiment(s):EBI-881656
Protein	ynbB		PMID:15690043^[7]	Experiment(s):EBI-889090
Protein	nrdA		PMID:15690043^[7]	Experiment(s):EBI-889090
Protein	ycjZ		PMID:15690043^[7]	Experiment(s):EBI-889090
Protein	nadE		PMID:16606699^[8]	Experiment(s):EBI-1142921
Protein	nrdA		PMID:19402753^[9]	LCMS(ID Probability):99.6
Protein	ynbB		PMID:19402753^[9]	LCMS(ID Probability):99.6
Protein	ycjZ		PMID:19402753^[9]	LCMS(ID Probability):99.6
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MDDQLKQSAL DFHEFPVPGK IQVSPTKPLA TQRDLALAYS PGVAAPCLEI EKDPLKAYKY TARGNLVAVI SNGTAVLGLG NIGALAGKPV MEGKGVLFKK FAGIDVFDIE VDELDPDKFI EVVAALEPTF GGINLEDIKA PECFYIEQKL RERMNIPVFH DDQHGTAIIS TAAILNGLRV VEKNISDVRM VVSGAGAAAI ACMNLLVALG LQKHNIVVCD SKGVIYQGRE PNMAETKAAY AVVDDGKRTL DDVIEGADIF LGCSGPKVLT QEMVKKMARA PMILALANPE PEILPPLAKE VRPDAIICTG RSDYPNQVNN VLCFPFIFRG ALDVGATAIN EEMKLAAVRA IAELAHAEQS EVVASAYGDQ DLSFGPEYII PKPFDPRLIV KIAPAVAKAA MESGVATRPI ADFDVYIDKL TEFVYKTNLF MKPIFSQARK APKRVVLPEG EEARVLHATQ ELVTLGLAKP ILIGRPNVIE MRIQKLGLQI KAGVDFEIVN NESDPRFKEY WTEYFQIMKR RGVTQEQAQR ALISNPTVIG AIMVQRGEAD AMICGTVGDY HEHFSVVKNV FGYRDGVHTA GAMNALLLPS GNTFIADTYV NDEPDAEELA EITLMAAETV RRFGIEPRVA LLSHSNFGSS DCPSSSKMRQ ALELVRERAP ELMIDGEMHG DAALVEAIRN DRMPDSSLKG SANILVMPNM EAARISYNLL RVSSSEGVTV GPVLMGVAKP VHVLTPIASV RRIVNMVALA VVEAQTQPL
Length	759
Mol. Wt	82.417 kDa
pI	5.3 (calculated)
Extinction coefficient	30,830 - 31,955 (calc based on 17 Y, 1 W, and 9 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	References
Domain	18..151	PF00390 Malic enzyme, N-terminal domain	PMID:19920124^[10]
Domain	163..401	PF03949 Malic enzyme, NAD binding domain	PMID:19920124^[10]
Domain	429..751	PF01515 Phosphate acetyl/butaryl transferase	PMID:19920124^[10]
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=maeB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:16130388	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:946947	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0008111	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P76558	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:G7293	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG14193	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:946947	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120003867	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB3945	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ van der Rest, ME et al. (2000) Functions of the membrane-associated and cytoplasmic malate dehydrogenases in the citric acid cycle of Escherichia coli. J. Bacteriol. 182 6892-9 PubMed
↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
↑ ^9.0 ^9.1 ^9.2 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
↑ ^10.0 ^10.1 ^10.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

maeB:Gene Product(s): Difference between revisions

Latest revision as of 20:51, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

@@ Line 35: / Line 35: @@
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 ****************************************************************************************** -->{{Product_nomenclature_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="H46aaa8f58949d"  class=" tableEdit Product_nomenclature_table"
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@@ Line 44: / Line 44: @@
 !align=left {{table heading style}} |Synonyms
 ||
-fused malic enzyme predicted oxidoreductase<ref name='LIB:Riley_2006'/>, predicted phosphotransacetylase<ref name='LIB:Riley_2006'/>, B2463<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YpfF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MaeB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
+''fused malic enzyme predicted oxidoreductase<ref name='LIB:Riley_2006'/>, predicted phosphotransacetylase<ref name='LIB:Riley_2006'/>, B2463<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YpfF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MaeB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2458, JW2447, ypfF, b2463''
 |-
 !align=left {{table heading style}} |Product description
@@ Line 52: / Line 52: @@
 Component of [[:Category:Complex:malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)|malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
+NADP-dependent malic enzyme; NADP-ME<ref name='LIB:EcoGene'/>
 |-
 !align=left {{table heading style}} |EC number (for enzymes)
 ||
-*
-|-class='sortbottom'
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.H46aaa8f58949d&page=25166&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.H46aaa8f58949d&page=25166&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.H46aaa8f58949d-->
-{{Product_nomenclature_help}}
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@@ Line 69: / Line 70: @@
 {{BacktoTop}}
 <protect>
-<big>'''Gene Ontology'''</big><br />{{Product_GO_help}}<!--box uid=421aa90e079fa326b6494f812ad13e79.25166.B46aaa8f709778-->
+<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.25166.B46aaa8f709778-->
 <!--
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 ****************************************************************************************** -->{{Product_GO_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="B46aaa8f709778"  class=" tableEdit GO_table_product dataTable"
 |- {{table_heading_style}}
-!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
+!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
 |-
 |
 |
-[[Category:GO:0005515_!_protein_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0005515_!_protein_binding GO:0005515]
+GO:0004473
+|
+malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
 |
-protein binding
+GOA:spec<br />GO_REF:0000003
-|[[PMID:16606699]]<ref name=PMID:16606699/>
 |
-IPI: Inferred from Physical Interaction
+IEA: Inferred from Electronic Annotation
 |
-[http://www.uniprot.org/uniprot/P18843 UniProtKB:P18843]
+EC:1.1.1.40
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 101: / Line 103: @@
 |
-[[Category:GO:0003824_!_catalytic_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003824_!_catalytic_activity GO:0003824]
+GO:0004473
 |
-catalytic activity
+malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
+PMID:11092847
 |
-IEA: Inferred from Electronic Annotation
+IMP: Inferred from Mutant Phenotype
 |
-[http://www.uniprot.org/keywords/KW-0511 SP_KW:KW-0511]
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+|
+GO:0005829
+|
+cytosol
+|
+PMID:16858726
+|
+IDA: Inferred from Direct Assay
+|
+|
+C
+|
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 120: / Line 141: @@
 |
-[[Category:GO:0004473_!_malate_dehydrogenase_(oxaloacetate-decarboxylating)_(NADP+)_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0004473_!_malate_dehydrogenase_(oxaloacetate-decarboxylating)_(NADP+)_activity GO:0004473]
+GO:0008152
 |
-malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
+metabolic process
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000003 GO_REF:0000003]
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.expasy.org/cgi-bin/nicezyme.pl?1.1.1.40 EC:1.1.1.40]
+InterPro:IPR002505
 |
-F
+P
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 139: / Line 160: @@
 |
-[[Category:GO:0008152_!_metabolic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008152_!_metabolic_process GO:0008152]
+GO:0008152
 |
 metabolic process
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR002505 InterPro:IPR002505]
+InterPro:IPR016040
 |
 P
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 158: / Line 179: @@
 |
-[[Category:GO:0008415_!_acyltransferase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008415_!_acyltransferase_activity GO:0008415]
+GO:0008415
 |
 acyltransferase activity
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR002505 InterPro:IPR002505]
+InterPro:IPR002505
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 177: / Line 198: @@
 |
-[[Category:GO:0016491_!_oxidoreductase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016491_!_oxidoreductase_activity GO:0016491]
+GO:0046872
 |
-oxidoreductase activity
+metal ion binding
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.uniprot.org/keywords/KW-0560 SP_KW:KW-0560]
+InterPro:IPR012188
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 196: / Line 217: @@
 |
-[[Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016616_!_oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor GO:0016616]
+GO:0046872
 |
-oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
+metal ion binding
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012188 InterPro:IPR012188]<br />[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012301 InterPro:IPR012301]<br />[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012302 InterPro:IPR012302]
+InterPro:IPR015884
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 215: / Line 236: @@
 |
-[[Category:GO:0046872_!_metal_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0046872_!_metal_ion_binding GO:0046872]
+GO:0046872
 |
 metal ion binding
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012188 InterPro:IPR012188]<br />[http://www.uniprot.org/keywords/KW-0479 SP_KW:KW-0479]
+SP_KW:KW-0479
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 234: / Line 255: @@
 |
-[[Category:GO:0051287_!_NAD_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0051287_!_NAD_binding GO:0051287]
+GO:0051287
 |
-NAD binding
+NAD or NADH binding
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR012302 InterPro:IPR012302]
+InterPro:IPR012302
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
 |-
 |
+|
+GO:0055114
+|
+oxidation reduction
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR012188
+|
+P
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+|
+GO:0055114
+|
+oxidation reduction
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR015884
+|
+P
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
 |
-[[Category:GO:0006094_!_gluconeogenesis]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006094_!_gluconeogenesis GO:0006094]
+GO:0055114
 |
-gluconeogenesis
+oxidation reduction
 |
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
+IEA: Inferred from Electronic Annotation
 |
+SP_KW:KW-0560
 |
 P
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
+Seeded from [[EcoCyc]] (v14.0)
 |
-required fields missing
+complete
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.B46aaa8f709778&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.B46aaa8f709778&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</span> || || || || || || || ||
 |}
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-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="Z46aaa8fa1c7a9"  class=" tableEdit Product_interactions_table dataTable"
 |- {{table heading style}}
 !|Partner Type!!Partner!!Notes!!References!!Evidence
@@ Line 289: / Line 348: @@
 Protein
 |
-[http://www.uniprot.org/uniprot/Subuni Subuni]ts of [[:Category:Complex:malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)|malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)]]
+Subunits of [[:Category:Complex:malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)|malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)]]
 |
 could be indirect
@@ Line 300: / Line 359: @@
 Protein
 |
-[[cca:Gene_Product(s)|cca]]<br />
+cca<br />
+|
+|
+PMID:15690043
+|
+Experiment(s):EBI-881656<br />
+|-
+|
+Protein
+|
+hrpA<br />
 |
-|[[PMID:15690043]]<ref name=PMID:15690043/>
 |
-Experiment(s):[http://www.ebi.ac.uk/iintact/search/do/search?searchString=EBI-881656 EBI-881656]<br />
+PMID:15690043
+|
+Experiment(s):EBI-881656<br />
 |-
 |
 Protein
 |
-[[hrpA:Gene_Product(s)|hrpA]]<br />
+ynbB<br />
 |
-|[[PMID:15690043]]<ref name=PMID:15690043/>
 |
-Experiment(s):[http://www.ebi.ac.uk/iintact/search/do/search?searchString=EBI-881656 EBI-881656]<br />
+PMID:15690043
+|
+Experiment(s):EBI-889090<br />
 |-
 |
 Protein
 |
-[[ynbB:Gene_Product(s)|ynbB]]<br />
+nrdA<br />
 |
-|[[PMID:15690043]]<ref name=PMID:15690043/>
 |
-Experiment(s):[http://www.ebi.ac.uk/iintact/search/do/search?searchString=EBI-889090 EBI-889090]<br />
+PMID:15690043
+|
+Experiment(s):EBI-889090<br />
 |-
 |
 Protein
 |
-[[nrdA:Gene_Product(s)|nrdA]]<br />
+ycjZ<br />
 |
-|[[PMID:15690043]]<ref name=PMID:15690043/>
 |
-Experiment(s):[http://www.ebi.ac.uk/iintact/search/do/search?searchString=EBI-889090 EBI-889090]<br />
+PMID:15690043
+|
+Experiment(s):EBI-889090<br />
 |-
 |
 Protein
 |
-[[ycjZ:Gene_Product(s)|ycjZ]]<br />
+nadE<br />
 |
-|[[PMID:15690043]]<ref name=PMID:15690043/>
 |
-Experiment(s):[http://www.ebi.ac.uk/iintact/search/do/search?searchString=EBI-889090 EBI-889090]<br />
+PMID:16606699
+|
+Experiment(s):EBI-1142921<br />
 |-
 |
 Protein
 |
-[[nadE:Gene_Product(s)|nadE]]<br />
+nrdA
 |
-|[[PMID:16606699]]<ref name=PMID:16606699/>
 |
-Experiment(s):[http://www.ebi.ac.uk/iintact/search/do/search?searchString=EBI-1142921 EBI-1142921]<br />
+PMID:19402753
+|
+LCMS(ID Probability):99.6
+|-
+|
+Protein
+|
+ynbB
+|
-|-class='sortbottom'
+|
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.Z46aaa8fa1c7a9&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
+PMID:19402753
+|
+LCMS(ID Probability):99.6
+|-
+|
+Protein
+|
+ycjZ
+|
+|
+PMID:19402753
+|
+LCMS(ID Probability):99.6
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.Z46aaa8fa1c7a9&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.Z46aaa8fa1c7a9-->
-{{Product_interactions_help}}
 <!--Function_notes--></protect>
 ===Notes===
@@ Line 374: / Line 472: @@
 *
 ****************************************************************************************** -->{{Product_localization_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="C46a8416fc7ccb"  class=" tableEdit Product_localization_table"
 |- {{table heading style}}
-!|Compartment!!Description!!Evidence!!Notes
+!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.C46a8416fc7ccb&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.C46a8416fc7ccb&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.C46a8416fc7ccb-->
-{{Product_localization_help}}
 <protect><!--Localization_notes--></protect>
@@ Line 399: / Line 497: @@
 *
 ****************************************************************************************** -->{{Product_physical_properties_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="F46aaa8fc741f2"  class=" tableEdit Product_phys_prop_table"
+|-
+!align=left {{table heading style}} |Name
+||
 |-
@@ Line 418: / Line 520: @@
 ELMIDGEMHG DAALVEAIRN DRMPDSSLKG SANILVMPNM EAARISYNLL RVSSSEGVTV
 GPVLMGVAKP VHVLTPIASV RRIVNMVALA VVEAQTQPL</pre>
+|-
+!align=left {{table heading style}} |Length
+||
 |-
 !align=left {{table heading style}} |Mol. Wt
 ||
-.42 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
+.417 kDa
 |-
 !align=left {{table heading style}} |pI
 ||
+.3 (calculated)
 |-
 !align=left {{table heading style}} |Extinction coefficient
 ||
-- 31955 (calc based on 17 Y, 1 W, and 9 C residues)
+,830 - 31,955 (calc based on 17 Y, 1 W, and 9 C residues)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.F46aaa8fc741f2&page=25166&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.F46aaa8fc741f2&page=25166&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.F46aaa8fc741f2-->
-{{Product_physical_properties_help}}
-<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
-<!--box uid=421aa90e079fa326b6494f812ad13e79.25166.L46aaa8fce2c24-->
+<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table>
+<tr align="left" valign="top">
+<td><!--box uid=421aa90e079fa326b6494f812ad13e79.25166.L46aaa8fce2c24-->
 <!--
 ******************************************************************************************
@@ Line 445: / Line 552: @@
 *
 ****************************************************************************************** -->{{Product_domains_motifs_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="L46aaa8fce2c24"  class=" tableEdit Product_motif_table dataTable"
 |- {{table heading style}}
-!|Type!!Residues!!Description!!Notes
+!|Type!!Residues!!Description!!Notes!!References
+|-
+|
+Domain
+|
+..151
+|
+[http://pfam.janelia.org/family/PF00390 PF00390  Malic enzyme, N-terminal domain]
+|
-|-class='sortbottom'
+|
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.L46aaa8fce2c24&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || ||
+PMID:19920124
+|-
+|
+Domain
+|
+..401
+|
+[http://pfam.janelia.org/family/PF03949 PF03949  Malic enzyme, NAD binding domain]
+|
+|
+PMID:19920124
+|-
+|
+Domain
+|
+..751
+|
+[http://pfam.janelia.org/family/PF01515 PF01515  Phosphate acetyl/butaryl transferase]
+|
+|
+PMID:19920124
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.L46aaa8fce2c24&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
 |}
-<!--box uid=421aa90e079fa326b6494f812ad13e79.25166.L46aaa8fce2c24-->
+<!--box uid=421aa90e079fa326b6494f812ad13e79.25166.L46aaa8fce2c24--></td>
-{{Product_domains_motifs_help}}
+<td>
+<!-- motifs column 2-->
+<motif_map/>
+</td>
+</tr>
+</table>
-<span id="Structure"></span><big>'''Structure'''</big>
+<table><tr valign='top'><td>
+<span id='Structure'></span><big>'''Structure'''</big><br />
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.Z46a84171966f4-->
 <!--
@@ Line 463: / Line 610: @@
 *
 ****************************************************************************************** -->{{Product_structure_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="Z46a84171966f4"  class=" tableEdit Product_structure_table"
 |-
 !align=left {{table heading style}} |Structures
 ||
-<beststructure>maeB
+<beststructure>
-</beststructure>
+gene=maeB
+taxon=562,83333
+</beststructure>
 |-
 !align=left {{table heading style}} |Models
 ||
 View models at:
-* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=maeB&sub=keywordSearc EcoliPredict]
+* [http://www.proteinmodelportal.org/query/uniprot/P36930 Protein Model Portal]
-* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=maeB&organism=562&organismtext= ModBase]
+* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P76558 PSI-PRED (P76558)]
-* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
+* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P76558 Genomes TO Protein (P76558)] (GTOP)
-* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
-* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.Z46a84171966f4&page=25166&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.Z46a84171966f4&page=25166&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.Z46a84171966f4-->
-{{Product_structure_help}}
-<!--Structure_notes--></protect>
+</td><td></protect>
+==== Structure figures ====
+<protect><!--          ***** PLEASE DO NOT EDIT BELOW THIS LINE *****         -->
+</td><tr><table><!--Structure_notes--></protect>
 ===Notes===
@@ Line 500: / Line 666: @@
 *
 ****************************************************************************************** -->{{Product_resources_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="O46aaa8fdaad13"  class=" tableEdit Product_resource_table"
 |- {{table_heading_style}}
 !|Resource type!!Source!!Notes/Reference
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.O46aaa8fdaad13&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.O46aaa8fdaad13&page=25166&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.O46aaa8fdaad13-->
-{{Product_resources_help}}
 <protect><!--Resources_notes--></protect>
 ===Notes===
@@ Line 522: / Line 688: @@
 *
 ****************************************************************************************** -->{{Gene_accessions_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="S46aaa8fe1460b"  class=" tableEdit Gene_accessions_table"
 |- {{table_heading_style}}
 !|Database!!Accession!!Notes
 |-
 |
-[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/16130388 GI:16130388]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/NP_416958.1 GeneID:946947]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[[ASAP]]
 |
-[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=MALIC-NADP-MONOMER EcoCyc:MALIC-NADP-MONOMER]
+ASAP:ABE-0008111
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
+|-
+|
+[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+|
+[http://www.uniprot.org/uniprot/P76558 UniProtKB/Swiss-Prot:P76558]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[[EcoCyc]]
+|
+EcoCyc:G7293
+|
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+[[EcoGene]]
 |
-[[uniprot:P76558|UniProt:P76558]]
+EcoGene:EG14193
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
 |
-[http://pfam.sanger.ac.uk/family?acc=PF00390 PFAM:PF00390]
+[http://www.ncbi.nlm.nih.gov/gene?term=946947 GeneID:946947]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
+[[RegulonDB]]
 |
-[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_416958 RefSeq:NP_416958]
+RegulonDB:ECK120003867
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
+[[EchoBASE]]
 |
-[http://salilab.org/modbase/searchbyid?databaseID=P76558 ModBase:P76558]
+EchoBASE:EB3945
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.S46aaa8fe1460b&page=25166&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.S46aaa8fe1460b&page=25166&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.S46aaa8fe1460b-->
-{{Product_accessions_help}}
 <protect><!--Accessions_notes--></protect>
 ===Notes===
@@ Line 579: / Line 773: @@
 *
 ****************************************************************************************** -->
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="T46a8417520a3d"  class=" tableEdit Links_table"
 |- {{table_heading_style}}
 !|Name!!URL!!Comments
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.T46a8417520a3d&page=25166&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25166.T46a8417520a3d&page=25166&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25166.T46a8417520a3d-->
-{{Links_help}}
@@ Line 595: / Line 789: @@
 {{BacktoTop}}
 {{RefHelp}}
-<references/>
+<references />
 __NOTOC__
-</noinclude>
 ===Categories===
 {{BacktoTop}}
 [[Category:Proteins]]
-[[Category:GO:0006094_!_gluconeogenesis]][[Category:Complex:malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)]]

maeB:Gene Product(s): Difference between revisions

Latest revision as of 20:51, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

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