cls:Gene Product(s): Difference between revisions

Standard name	Cls
Synonyms	cardiolipin synthase 1^[1], B1249^[2]^[1], YciJ^[2]^[1], Nov^[2]^[1], Cls^[2]^[1] , ECK1243, JW1241, nov, yciJ, b1249
Product description	Cardiolipin synthase; mutants dihydroxybutylphosphonate resistant; novobiocin sensitivity^[3]
EC number (for enzymes)	2.7.8.-^[1]
edit table

Notes

Function

[back to top]

Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005886	plasma membrane	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00190	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C	Seeded from EcoCyc (v14.0)	complete
	GO:0008152	metabolic process	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001736	P	Seeded from EcoCyc (v14.0)	complete
	GO:0008654	phospholipid biosynthetic process	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00190	P	Seeded from EcoCyc (v14.0)	complete
	GO:0008654	phospholipid biosynthetic process	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0594	P	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-9909	C	Seeded from EcoCyc (v14.0)	complete
	GO:0008808	cardiolipin synthase activity	PMID:353047^[4]	IMP: Inferred from Mutant Phenotype		F		complete
edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
edit table

Notes

Required for synthesis of cardiolipin.

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
plasma membrane			From EcoCyc^[5]
edit table

Notes

Structure and Physical Properties

[back to top]

Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MTTVYTLVSW LAILGYWLLI AGVTLRILMK RRAVPSAMAW LLIIYILPLV GIIAYLAVGE LHLGKRRAER ARAMWPSTAK WLNDLKACKH IFAEENSSVA APLFKLCERR QGIAGVKGNQ LQLMTESDDV MQALIRDIQL ARHNIEMVFY IWQPGGMADQ VAESLMAAAR RGIHCRLMLD SAGSVAFFRS PWPELMRNAG IEVVEALKVN LMRVFLRRMD LRQHRKMIMI DNYIAYTGSM NMVDPRYFKQ DAGVGQWIDL MARMEGPIAT AMGIIYSCDW EIETGKRILP PPPDVNIMPF EQASGHTIHT IASGPGFPED LIHQALLTAA YSAREYLIMT TPYFVPSDDL LHAICTAAQR GVDVSIILPR KNDSMLVGWA SRAFFTELLA AGVKIYQFEG GLLHTKSVLV DGELSLVGTV NLDMRSLWLN FEITLAIDDK GFGADLAAVQ DDYISRSRLL DARLWLKRPL WQRVAERLFY FFSPLL
Length	486
Mol. Wt	54.824 kDa
pI	8.4 (calculated)
Extinction coefficient	93,850 - 94,475 (calc based on 15 Y, 13 W, and 5 C residues)
edit table

Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	References
Domain	219..246	PF00614 Phospholipase D Active site motif	PMID:19920124^[6]
Domain	399..426	PF00614 Phospholipase D Active site motif	PMID:19920124^[6]
edit table

<motif_map/>

Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=cls taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

Gene Product Resources

[back to top]

See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
edit table

Notes

Accessions in Other Databases

[back to top]

See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:16129210	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:945821	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P0A6H8	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:945821	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:	Escherichia coli str. K-12 substr. MG1655
edit table

Notes

Links

[back to top]

Name	URL	Comments
edit table

References

[back to top]

See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ Pluschke, G et al. (1978) Function of phospholipids in Escherichia coli. Characterization of a mutant deficient in cardiolipin synthesis. J. Biol. Chem. 253 5048-55 PubMed
↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^6.0 ^6.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

cls:Gene Product(s): Difference between revisions

Latest revision as of 20:36, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

@@ Line 34: / Line 34: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Product_nomenclature_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="V46aa5f7651ffb"  class=" tableEdit Product_nomenclature_table"
 |-
@@ Line 44: / Line 44: @@
 !align=left {{table heading style}} |Synonyms
 ||
-cardiolipin synthase 1<ref name='LIB:Riley_2006'/>, B1249<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YciJ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nov product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cls product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
+''cardiolipin synthase 1<ref name='LIB:Riley_2006'/>, B1249<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YciJ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nov<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cls<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1243, JW1241, nov, yciJ, b1249''
 |-
 !align=left {{table heading style}} |Product description
 ||
-CARDIOLIPSYN-MONOMER<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
+Cardiolipin synthase; mutants dihydroxybutylphosphonate resistant; novobiocin sensitivity<ref name='LIB:EcoGene'/>
 |-
 !align=left {{table heading style}} |EC number (for enzymes)
 ||
-* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.- 2.7.8.-]<ref name='LIB:Riley_2006'/>
+ [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.- 2.7.8.-]<ref name='LIB:Riley_2006'/>
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.V46aa5f7651ffb&page=22455&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.V46aa5f7651ffb&page=22455&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.V46aa5f7651ffb-->
-{{Product_nomenclature_help}}
 <protect><!--Nomenclature_notes--></protect>
 ===Notes===
@@ Line 67: / Line 67: @@
 {{BacktoTop}}
 <protect>
-<big>'''Gene Ontology'''</big><br />{{Product_GO_help}}<!--box uid=421aa90e079fa326b6494f812ad13e79.22455.T46aa5f775286b-->
+<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.22455.T46aa5f775286b-->
 <!--
 ******************************************************************************************
@@ Line 73: / Line 73: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Product_GO_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="T46aa5f775286b"  class=" tableEdit GO_table_product dataTable"
 |- {{table_heading_style}}
-!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
+!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
 |-
 |
 |
-[[Category:GO:0016740_!_transferase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016740_!_transferase_activity GO:0016740]
+GO:0005886
 |
-transferase activity
+plasma membrane
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
+GOA:hamap<br />GO_REF:0000020
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.uniprot.org/keywords/KW-0808 SP_KW:KW-0808]
+HAMAP:MF_00190
 |
-F
+C
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 100: / Line 100: @@
 |
-[[Category:GO:0016021_!_integral_to_membrane]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016021_!_integral_to_membrane GO:0016021]
+GO:0005886
 |
-integral to membrane
+plasma membrane
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.uniprot.org/keywords/KW-0812 SP_KW:KW-0812]
+SP_KW:KW-0997
 |
 C
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 119: / Line 119: @@
 |
-[[Category:GO:0016020_!_membrane]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016020_!_membrane GO:0016020]
+GO:0005886
 |
-membrane
+plasma membrane
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]<br />GO_REF:0000004
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.uniprot.org/keywords/KW-0397 SP_KW:KW-0397]<br />[http://www.uniprot.org/keywords/KW-0472 SP_KW:KW-0472]
+SP_KW:KW-1003
 |
 C
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+|
+GO:0008152
+|
+metabolic process
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR001736
+|
+P
+|
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 138: / Line 157: @@
 |
-[[Category:GO:0008654_!_phospholipid_biosynthetic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008654_!_phospholipid_biosynthetic_process GO:0008654]
+GO:0008654
 |
 phospholipid biosynthetic process
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]<br />GO_REF:0000020
+GOA:hamap<br />GO_REF:0000020
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.uniprot.org/keywords/KW-0594 SP_KW:KW-0594]<br />HAMAP:MF_00190
+HAMAP:MF_00190
 |
 P
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 157: / Line 176: @@
 |
-[[Category:GO:0008152_!_metabolic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008152_!_metabolic_process GO:0008152]
+GO:0008654
 |
-metabolic process
+phospholipid biosynthetic process
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR001736 [http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR001736 InterPro:IPR001736]]
+SP_KW:KW-0594
 |
 P
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 176: / Line 195: @@
 |
-[[Category:GO:0003824_!_catalytic_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003824_!_catalytic_activity GO:0003824]
+GO:0016020
 |
-catalytic activity
+membrane
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR001736 [http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR001736 InterPro:IPR001736]]
+SP_KW:KW-0472
 |
-F
+C
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
 |-
 |
 |
-[[Category:GO:0042493_!_response_to_drug]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0042493_!_response_to_drug GO:0042493]
+GO:0016021
 |
-response to drug
+integral to membrane
 |
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
+IEA: Inferred from Electronic Annotation
 |
+SP_KW:KW-0812
 |
-P
+C
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
+Seeded from [[EcoCyc]] (v14.0)
 |
-required fields missing
+complete
 |-
 |
 |
-[[Category:GO:0008808_!_cardiolipin_synthase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008808_!_cardiolipin_synthase_activity GO:0008808]
+GO:0016021
 |
-cardiolipin synthase activity
+integral to membrane
 |
-[[PMID:353047]]<ref name=PMID:353047/>
+GO_REF:0000023
 |
-IMP: Inferred from Mutant Phenotype
+IEA: Inferred from Electronic Annotation
 |
+SP_SL:SL-9909
 |
-F
+C
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 233: / Line 252: @@
 |
-[[Category:GO:0016780_!_phosphotransferase_activity,_for_other_substituted_phosphate_groups]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016780_!_phosphotransferase_activity,_for_other_substituted_phosphate_groups GO:0016780]
+GO:0008808
 |
-phosphotransferase activity, for other substituted phosphate groups
+cardiolipin synthase activity
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000020 GO_REF:0000020]
+PMID:353047
 |
-IEA: Inferred from Electronic Annotation
+IMP: Inferred from Mutant Phenotype
 |
-HAMAP:MF_00190
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
 |
 complete
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.T46aa5f775286b&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.T46aa5f775286b&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</span> || || || || || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.T46aa5f775286b-->
@@ Line 261: / Line 280: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Product_interactions_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="O46aa5f85a6725"  class=" tableEdit Product_interactions_table dataTable"
 |- {{table heading style}}
-!|Partner Type!!Partner!!Notes
+!|Partner Type!!Partner!!Notes!!References!!Evidence
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.O46aa5f85a6725&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.O46aa5f85a6725&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.O46aa5f85a6725-->
-{{Product_interactions_help}}
 <!--Function_notes--></protect>
 ===Notes===
@@ Line 282: / Line 301: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Product_localization_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="D46aa5f865b450"  class=" tableEdit Product_localization_table"
 |- {{table heading style}}
-!|Compartment!!Description!!Evidence!!Notes
+!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
 |-
 |
@@ Line 294: / Line 313: @@
 |
 From EcoCyc<ref name='LIB:EcoCyc11.1'/>
+|
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.D46aa5f865b450&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.D46aa5f865b450&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.D46aa5f865b450-->
-{{Product_localization_help}}
 <protect><!--Localization_notes--></protect>
@@ Line 316: / Line 337: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Product_physical_properties_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="C46aa5f87c8cd1"  class=" tableEdit Product_phys_prop_table"
+|-
+!align=left {{table heading style}} |Name
+||
 |-
@@ Line 332: / Line 357: @@
 NLDMRSLWLN FEITLAIDDK GFGADLAAVQ DDYISRSRLL DARLWLKRPL WQRVAERLFY
 FFSPLL</pre>
+|-
+!align=left {{table heading style}} |Length
+||
 |-
 !align=left {{table heading style}} |Mol. Wt
 ||
-.82 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
+.824 kDa
 |-
 !align=left {{table heading style}} |pI
 ||
+.4 (calculated)
 |-
 !align=left {{table heading style}} |Extinction coefficient
 ||
-- 94475 (calc based on 15 Y, 13 W, and 5 C residues)
+,850 - 94,475 (calc based on 15 Y, 13 W, and 5 C residues)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.C46aa5f87c8cd1&page=22455&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.C46aa5f87c8cd1&page=22455&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.C46aa5f87c8cd1-->
-{{Product_physical_properties_help}}
 <span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
@@ Line 362: / Line 391: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Product_domains_motifs_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="A46aa5f88317e6"  class=" tableEdit Product_motif_table dataTable"
 |- {{table heading style}}
-!|Type!!Residues!!Description!!Notes
+!|Type!!Residues!!Description!!Notes!!References
 |-
 |
 Domain
 |
-- 246
+..246
 |
-[[interpro:IPR001736|PLD phosphodiesterase 1]]
+[http://pfam.janelia.org/family/PF00614 PF00614  Phospholipase D Active site motif]
 |
-[http://www.uniprot.org/uniprot/P0A6H8#section_features UniProt:P0A6H8]
-|-
-|
-Domain
-|
-- 426
-|
-[[interpro:IPR001736|PLD phosphodiesterase 2]]
 |
-[http://www.uniprot.org/uniprot/P0A6H8#section_features UniProt:P0A6H8]
+PMID:19920124
 |-
 |
 Domain
 |
-- 29
+..426
 |
-Predicted membrane-spanning helix.
+[http://pfam.janelia.org/family/PF00614 PF00614  Phospholipase D Active site motif]
 |
-TMD predicted by [http://www.cbs.dtu.dk/services/TMHMM TMHMM]<ref name='PMID:11152613' />
-|-
-|
-Domain
-|
-- 58
-|
-Predicted membrane-spanning helix.
 |
-TMD predicted by [http://www.cbs.dtu.dk/services/TMHMM TMHMM]<ref name='PMID:11152613' />
+PMID:19920124
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.A46aa5f88317e6&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.A46aa5f88317e6&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.A46aa5f88317e6-->
-{{Product_domains_motifs_help}}
 </td>
 <td>
+<!-- motifs column 2-->
+<motif_map/>
 {{TMHMM Picture|cls}}
 </td>
@@ Line 415: / Line 433: @@
 </table>
-<span id="Structure"></span><big>'''Structure'''</big>
+<table><tr valign='top'><td>
+<span id='Structure'></span><big>'''Structure'''</big><br />
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.A46a7f26810b00-->
 <!--
@@ Line 422: / Line 441: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Product_structure_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="A46a7f26810b00"  class=" tableEdit Product_structure_table"
 |-
 !align=left {{table heading style}} |Structures
 ||
-<beststructure>cls
+<beststructure>
-</beststructure>
+gene=cls
+taxon=562,83333
+</beststructure>
 |-
 !align=left {{table heading style}} |Models
 ||
 View models at:
-* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=cls&sub=keywordSearc EcoliPredict]
+* [http://www.proteinmodelportal.org/query/uniprot/P0A6H8 Protein Model Portal]
-* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=cls&organism=562&organismtext= ModBase]
+* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0A6H8 PSI-PRED (P0A6H8)]
-* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
+* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0A6H8 Genomes TO Protein (P0A6H8)] (GTOP)
-* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
-* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.A46a7f26810b00&page=22455&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.A46a7f26810b00&page=22455&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.A46a7f26810b00-->
-{{Product_structure_help}}
-<!--Structure_notes--></protect>
+</td><td></protect>
+==== Structure figures ====
+<protect><!--          ***** PLEASE DO NOT EDIT BELOW THIS LINE *****         -->
+</td><tr><table><!--Structure_notes--></protect>
 ===Notes===
@@ Line 459: / Line 497: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Product_resources_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="V46aa5f88cca52"  class=" tableEdit Product_resource_table"
 |- {{table_heading_style}}
 !|Resource type!!Source!!Notes/Reference
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.V46aa5f88cca52&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.V46aa5f88cca52&page=22455&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.V46aa5f88cca52-->
-{{Product_resources_help}}
 <protect><!--Resources_notes--></protect>
 ===Notes===
@@ Line 481: / Line 519: @@
 *   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
-****************************************************************************************** -->
+****************************************************************************************** -->{{Gene_accessions_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="J46aa5f89259c0"  class=" tableEdit Gene_accessions_table"
 |- {{table_heading_style}}
 !|Database!!Accession!!Notes
 |-
 |
-[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/16129210 GI:16129210]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
 |
-[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=CARDIOLIPSYN-MONOMER EcoCyc:CARDIOLIPSYN-MONOMER]
+[http://www.ncbi.nlm.nih.gov/protein/NP_415765.1 GeneID:945821]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
 |
-[[uniprot:P0A6H8|UniProt:P0A6H8]]
+[http://www.uniprot.org/uniprot/P0A6H8 UniProtKB/Swiss-Prot:P0A6H8]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
 |
-[http://pfam.sanger.ac.uk/family?acc=PF00614 PFAM:PF00614]
+[http://www.ncbi.nlm.nih.gov/gene?term=945821 GeneID:945821]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
+[[RegulonDB]]
 |
-[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415765 RefSeq:NP_415765]
+RegulonDB:
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
+[[EchoBASE]]
 |
-[http://salilab.org/modbase/searchbyid?databaseID=P0A6H8 ModBase:P0A6H8]
+EchoBASE:
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.J46aa5f89259c0&page=22455&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.J46aa5f89259c0&page=22455&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.J46aa5f89259c0-->
-{{Product_accessions_help}}
 <protect><!--Accessions_notes--></protect>
 ===Notes===
@@ Line 539: / Line 584: @@
 *
 ****************************************************************************************** -->
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="V46a7f26b6fad1"  class=" tableEdit Links_table"
 |- {{table_heading_style}}
 !|Name!!URL!!Comments
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.V46a7f26b6fad1&page=22455&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22455.V46a7f26b6fad1&page=22455&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.22455.V46a7f26b6fad1-->
-{{Links_help}}
@@ Line 555: / Line 600: @@
 {{BacktoTop}}
 {{RefHelp}}
-<references/>
+<references />
 __NOTOC__
-</noinclude>
 ===Categories===
 {{BacktoTop}}
 [[Category:Proteins]]
-[[Category:GO:0016021_!_integral to membrane]][[Category:GO:0008654_!_phospholipid biosynthetic process]][[Category:GO:0042493_!_response to drug]][[Category:Location:plasma membrane]]

cls:Gene Product(s): Difference between revisions

Latest revision as of 20:36, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

Search