mfd:Gene Product(s): Difference between revisions
No edit summary |
touch table |
||
| (39 intermediate revisions by 5 users not shown) | |||
| Line 35: | Line 35: | ||
* | * | ||
****************************************************************************************** -->{{Product_nomenclature_help}} | ****************************************************************************************** -->{{Product_nomenclature_help}} | ||
{| | {| id="Z46aa57857e25d" class=" tableEdit Product_nomenclature_table" | ||
|- | |- | ||
| Line 44: | Line 44: | ||
!align=left {{table heading style}} |Synonyms | !align=left {{table heading style}} |Synonyms | ||
|| | || | ||
transcription-repair coupling factor<ref name='LIB:Riley_2006'/>, B1114<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mfd<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TRCF<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/> | ''transcription-repair coupling factor<ref name='LIB:Riley_2006'/>, B1114<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mfd<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TRCF<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/> , ECK1100, JW1100, b1114'' | ||
|- | |- | ||
!align=left {{table heading style}} |Product description | !align=left {{table heading style}} |Product description | ||
| Line 56: | Line 56: | ||
|-class= | |- class="tableEdit_footer" | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Z46aa57857e25d&page=22136&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] || | |<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Z46aa57857e25d&page=22136&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table]</span> || | ||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Z46aa57857e25d--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Z46aa57857e25d--> | ||
| Line 75: | Line 75: | ||
* | * | ||
****************************************************************************************** -->{{Product_GO_help}} | ****************************************************************************************** -->{{Product_GO_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="P46aa57867c376" class=" tableEdit GO_table_product dataTable" | ||
|- {{table_heading_style}} | |- {{table_heading_style}} | ||
!|Qualifier!!GO ID!!GO term name!!Reference | !|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status | ||
|- | |- | ||
| | | | ||
| | | | ||
GO: | GO:0006281 | ||
| | | | ||
DNA repair | |||
| | | | ||
PMID: | PMID:1763073 | ||
| | | | ||
IMP: Inferred from Mutant Phenotype | |||
| | | | ||
| | | | ||
P | |||
| | | | ||
| | | | ||
complete | complete | ||
| Line 101: | Line 101: | ||
| | | | ||
GO: | GO:0006355 | ||
| | | | ||
regulation of transcription, DNA-dependent | |||
| | | | ||
PMID:8465200 | |||
| | | | ||
IDA: Inferred from Direct Assay | |||
| | | | ||
| | | | ||
P | |||
| | | | ||
| | | | ||
complete | complete | ||
| Line 120: | Line 120: | ||
| | | | ||
GO: | GO:0006974 | ||
| | | | ||
response to DNA damage stimulus | |||
| | | | ||
PMID:8465200 | |||
| | | | ||
IDA: Inferred from Direct Assay | |||
| | | | ||
| | | | ||
P | |||
| | | | ||
| | | | ||
complete | complete | ||
| Line 139: | Line 139: | ||
| | | | ||
GO: | GO:0000716 | ||
| | | | ||
DNA | transcription-coupled nucleotide-excision repair, DNA damage recognition | ||
| | | | ||
PMID:8465200 | |||
| | | | ||
IDA: Inferred from Direct Assay | |||
| | | | ||
| | | | ||
P | |||
| | | | ||
| | | | ||
complete | complete | ||
| Line 158: | Line 158: | ||
| | | | ||
GO: | GO:0000166 | ||
| | | | ||
nucleotide binding | |||
| | | | ||
GO_REF: | GOA:spkw<br />SP_KW:GO_REF:0000004 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW-0547 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 177: | Line 177: | ||
| | | | ||
GO: | GO:0003676 | ||
| | | | ||
nucleic acid binding | |||
| | | | ||
GO_REF:0000002 | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro: | InterPro:IPR001650 | ||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 196: | Line 196: | ||
| | | | ||
GO: | GO:0003676 | ||
| | | | ||
nucleic acid binding | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro: | InterPro:IPR011545 | ||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 215: | Line 215: | ||
| | | | ||
GO: | GO:0003677 | ||
| | | | ||
DNA binding | |||
| | | | ||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW-0238 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 234: | Line 234: | ||
| | | | ||
GO: | GO:0003684 | ||
| | | | ||
DNA | damaged DNA binding | ||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR004576 | InterPro:IPR004576 | ||
| | | | ||
F | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 253: | Line 253: | ||
| | | | ||
GO: | GO:0003684 | ||
| | | | ||
damaged DNA binding | |||
| | | | ||
GO_REF:0000002 | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro: | InterPro:IPR005118 | ||
| | | | ||
F | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 272: | Line 272: | ||
| | | | ||
GO: | GO:0003700 | ||
| | | | ||
transcription factor activity | |||
| | | | ||
GO_REF: | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR003711 | |||
| | | | ||
F | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 291: | Line 291: | ||
| | | | ||
GO: | GO:0004386 | ||
| | | | ||
helicase activity | |||
| | | | ||
GO_REF:0000002 | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro: | InterPro:IPR001650 | ||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 310: | Line 310: | ||
| | | | ||
GO: | GO:0004386 | ||
| | | | ||
helicase activity | |||
| | | | ||
GO_REF: | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR004576 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
|- | |- | ||
| | | | ||
| | | | ||
GO: | GO:0004386 | ||
| | | | ||
helicase activity | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
InterPro:IPR005118 | |||
| | | | ||
F | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | |||
|- | |- | ||
| | | | ||
| | | | ||
GO: | GO:0004386 | ||
| | | | ||
helicase activity | |||
| | | | ||
GO_REF:0000004 | GOA:spkw<br />SP_KW:GO_REF:0000004 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW- | SP_KW:KW-0347 | ||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 367: | Line 367: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR001650 | InterPro:IPR001650 | ||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 386: | Line 386: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GO_REF: | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR004576 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 405: | Line 405: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR005118 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 424: | Line 424: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GO_REF:0000002 | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro: | InterPro:IPR011545 | ||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 443: | Line 443: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW-0067 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 462: | Line 462: | ||
| | | | ||
GO: | GO:0006281 | ||
| | | | ||
DNA repair | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
InterPro:IPR004576 | |||
| | | | ||
P | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 481: | Line 481: | ||
| | | | ||
GO: | GO:0006281 | ||
| | | | ||
DNA repair | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR005118 | |||
| | | | ||
P | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 504: | Line 504: | ||
DNA repair | DNA repair | ||
| | | | ||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW-0234 | |||
| | | | ||
P | P | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 523: | Line 523: | ||
regulation of transcription, DNA-dependent | regulation of transcription, DNA-dependent | ||
| | | | ||
GO_REF:0000002 | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| Line 531: | Line 531: | ||
P | P | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 542: | Line 542: | ||
response to DNA damage stimulus | response to DNA damage stimulus | ||
| | | | ||
GO_REF:0000004 | GOA:spkw<br />SP_KW:GO_REF:0000004 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| Line 550: | Line 550: | ||
P | P | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 561: | Line 561: | ||
ATP-dependent helicase activity | ATP-dependent helicase activity | ||
| | | | ||
GO_REF:0000002 | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| Line 569: | Line 569: | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 580: | Line 580: | ||
hydrolase activity | hydrolase activity | ||
| | | | ||
GO_REF:0000004 | GOA:spkw<br />SP_KW:GO_REF:0000004 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| Line 588: | Line 588: | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
|-class= | |- class="tableEdit_footer" | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.P46aa57867c376&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || || | |<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.P46aa57867c376&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</span> || || || || || || || || | ||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.P46aa57867c376--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.P46aa57867c376--> | ||
| Line 624: | Line 605: | ||
* | * | ||
****************************************************************************************** -->{{Product_interactions_help}} | ****************************************************************************************** -->{{Product_interactions_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aa578d15fd5" class=" tableEdit Product_interactions_table dataTable" | ||
|- {{table heading style}} | |- {{table heading style}} | ||
!|Partner Type!!Partner!!Notes!!References!!Evidence | !|Partner Type!!Partner!!Notes!!References!!Evidence | ||
| Line 715: | Line 696: | ||
| | | | ||
Experiment(s):EBI-1138903<br /> | Experiment(s):EBI-1138903<br /> | ||
|- | |||
| | |||
Protein | |||
| | |||
tdcC | |||
| | |||
|-class= | | | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578d15fd5&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || || | PMID:19402753 | ||
| | |||
LCMS(ID Probability):99.0 | |||
|- | |||
| | |||
Protein | |||
| | |||
yffB | |||
| | |||
| | |||
PMID:19402753 | |||
| | |||
LCMS(ID Probability):99.0 | |||
|- class="tableEdit_footer" | |||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578d15fd5&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || || | |||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578d15fd5--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578d15fd5--> | ||
| Line 733: | Line 736: | ||
* | * | ||
****************************************************************************************** -->{{Product_localization_help}} | ****************************************************************************************** -->{{Product_localization_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="B46a7ea7d8df88" class=" tableEdit Product_localization_table" | ||
|- {{table heading style}} | |- {{table heading style}} | ||
!|Compartment!!Description!!Evidence!!Notes | !|Compartment!!Description!!Evidence!!Reference/Source!!Notes | ||
|-class= | |- class="tableEdit_footer" | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.B46a7ea7d8df88&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || | |<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.B46a7ea7d8df88&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || || | ||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.B46a7ea7d8df88--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.B46a7ea7d8df88--> | ||
| Line 758: | Line 761: | ||
* | * | ||
****************************************************************************************** -->{{Product_physical_properties_help}} | ****************************************************************************************** -->{{Product_physical_properties_help}} | ||
{| | {| id="Y46aa578ed0dad" class=" tableEdit Product_phys_prop_table" | ||
|- | |||
!align=left {{table heading style}} |Name | |||
|| | |||
|- | |- | ||
| Line 801: | Line 808: | ||
95,230 - 96,105 (calc based on 27 Y, 10 W, and 7 C residues) | 95,230 - 96,105 (calc based on 27 Y, 10 W, and 7 C residues) | ||
|-class= | |- class="tableEdit_footer" | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578ed0dad&page=22136&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] || | |<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578ed0dad&page=22136&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> || | ||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578ed0dad--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578ed0dad--> | ||
| Line 816: | Line 823: | ||
* | * | ||
****************************************************************************************** -->{{Product_domains_motifs_help}} | ****************************************************************************************** -->{{Product_domains_motifs_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aa578f398c3" class=" tableEdit Product_motif_table dataTable" | ||
|- {{table heading style}} | |- {{table heading style}} | ||
!|Type!!Residues!!Description!!Notes | !|Type!!Residues!!Description!!Notes!!References | ||
|- | |||
| | |||
Domain | |||
| | |||
602..766 | |||
| | |||
[http://pfam.janelia.org/family/PF00270 PF00270 DEAD/DEAH box helicase] | |||
| | |||
|-class= | | | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578f398c3&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || | PMID:19920124 | ||
|- | |||
| | |||
Domain | |||
| | |||
832..907 | |||
| | |||
[http://pfam.janelia.org/family/PF00271 PF00271 Helicase conserved C-terminal domain] | |||
| | |||
| | |||
PMID:19920124 | |||
|- | |||
| | |||
Domain | |||
| | |||
476..573 | |||
| | |||
[http://pfam.janelia.org/family/PF02559 PF02559 CarD-like/TRCF domain] | |||
| | |||
| | |||
PMID:19920124 | |||
|- | |||
| | |||
Domain | |||
| | |||
1005..1105 | |||
| | |||
[http://pfam.janelia.org/family/PF03461 PF03461 TRCF domain] | |||
| | |||
| | |||
PMID:19920124 | |||
|- class="tableEdit_footer" | |||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578f398c3&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || || | |||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578f398c3--></td> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Y46aa578f398c3--></td> | ||
| Line 841: | Line 892: | ||
* | * | ||
****************************************************************************************** -->{{Product_structure_help}} | ****************************************************************************************** -->{{Product_structure_help}} | ||
{| | {| id="Z46aa578f86356" class=" tableEdit Product_structure_table" | ||
|- | |- | ||
| Line 854: | Line 905: | ||
|| | || | ||
View models at: | View models at: | ||
* [http:// | * [http://www.proteinmodelportal.org/query/uniprot/P30958 Protein Model Portal] | ||
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P30958 PSI-PRED (P30958)] | |||
* [http://bioinf.cs.ucl.ac.uk/ | * [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P30958 Genomes TO Protein (P30958)] (GTOP) | ||
* [http://spock.genes.nig.ac.jp/~genome/ | |||
|-class= | |- class="tableEdit_footer" | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Z46aa578f86356&page=22136&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] || | |<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Z46aa578f86356&page=22136&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> || | ||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Z46aa578f86356--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Z46aa578f86356--> | ||
| Line 899: | Line 948: | ||
* | * | ||
****************************************************************************************** -->{{Product_resources_help}} | ****************************************************************************************** -->{{Product_resources_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="U46aa5790c2646" class=" tableEdit Product_resource_table" | ||
|- {{table_heading_style}} | |- {{table_heading_style}} | ||
!|Resource type!!Source!!Notes/Reference | !|Resource type!!Source!!Notes/Reference | ||
|-class= | |- class="tableEdit_footer" | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.U46aa5790c2646&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || || | |<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.U46aa5790c2646&page=22136&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || || | ||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.U46aa5790c2646--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.U46aa5790c2646--> | ||
| Line 921: | Line 970: | ||
* | * | ||
****************************************************************************************** -->{{Gene_accessions_help}} | ****************************************************************************************** -->{{Gene_accessions_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46aa57911b787" class=" tableEdit Gene_accessions_table" | ||
|- {{table_heading_style}} | |- {{table_heading_style}} | ||
!|Database!!Accession!!Notes | !|Database!!Accession!!Notes | ||
|- | |- | ||
| | | | ||
[http:// | [http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]]) | ||
| | |||
[http://www.ncbi.nlm.nih.gov/protein/16129077 GI:16129077] | |||
| | |||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
| | |||
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]]) | |||
| | |||
[http://www.ncbi.nlm.nih.gov/protein/NP_415632.1 GeneID:945681] | |||
| | | | ||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
| | | | ||
[[ASAP]] | |||
| | |||
ASAP:ABE-0003763 | |||
| | |||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[http:// | [http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]]) | ||
| | | | ||
[http:// | [http://www.uniprot.org/uniprot/P30958 UniProtKB/Swiss-Prot:P30958] | ||
| | | | ||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |- | ||
| | | | ||
[[EcoCyc]] | |||
| | | | ||
EcoCyc:EG11619 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[[EcoGene]] | |||
| | | | ||
EcoGene:EG11619 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[http://www.ncbi.nlm.nih.gov/ | [http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]]) | ||
| | | | ||
[http://www.ncbi.nlm.nih.gov/ | [http://www.ncbi.nlm.nih.gov/gene?term=945681 GeneID:945681] | ||
| | | | ||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |- | ||
| | | | ||
[[RegulonDB]] | |||
| | | | ||
RegulonDB:ECK120001567 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[[EchoBASE]] | |||
| | | | ||
EchoBASE:EB1576 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|-class= | |- class="tableEdit_footer" | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.W46aa57911b787&page=22136&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || || | |<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.W46aa57911b787&page=22136&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table]</span> || || | ||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.W46aa57911b787--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.W46aa57911b787--> | ||
| Line 992: | Line 1,055: | ||
* | * | ||
****************************************************************************************** --> | ****************************************************************************************** --> | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Q46a7ea85c5f14" class=" tableEdit Links_table" | ||
|- {{table_heading_style}} | |- {{table_heading_style}} | ||
!|Name!!URL!!Comments | !|Name!!URL!!Comments | ||
|-class= | |- class="tableEdit_footer" | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Q46a7ea85c5f14&page=22136&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || || | |<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.22136.Q46a7ea85c5f14&page=22136&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table]</span> || || | ||
|} | |} | ||
<!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Q46a7ea85c5f14--> | <!--box uid=421aa90e079fa326b6494f812ad13e79.22136.Q46a7ea85c5f14--> | ||
| Line 1,013: | Line 1,076: | ||
{{BacktoTop}} | {{BacktoTop}} | ||
[[Category:Proteins]] | [[Category:Proteins]] | ||
Latest revision as of 20:34, 17 February 2015
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
Mfd |
|---|---|
| Synonyms |
transcription-repair coupling factor[1], B1114[2][1], Mfd[2][1], TRCF[3][1] , ECK1100, JW1100, b1114 |
| Product description |
transcription-repair coupling factor[2][3] Transcription repair coupling factor[4] |
| EC number (for enzymes) |
|
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0006281 |
DNA repair |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0006974 |
response to DNA damage stimulus |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0000716 |
transcription-coupled nucleotide-excision repair, DNA damage recognition |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0000166 |
nucleotide binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003676 |
nucleic acid binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003676 |
nucleic acid binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003684 |
damaged DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003684 |
damaged DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004386 |
helicase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004386 |
helicase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004386 |
helicase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004386 |
helicase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006355 |
regulation of transcription, DNA-dependent |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006974 |
response to DNA damage stimulus |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0008026 |
ATP-dependent helicase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016787 |
hydrolase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
tdcC |
Experiment(s):EBI-893742 | ||
|
Protein |
yffB |
Experiment(s):EBI-893742 | ||
|
Protein |
ihfA |
Experiment(s):EBI-1138903 | ||
|
Protein |
rpsM |
Experiment(s):EBI-1138903 | ||
|
Protein |
yeeT |
Experiment(s):EBI-1138903 | ||
|
Protein |
rplB |
Experiment(s):EBI-1138903 | ||
|
Protein |
stpA |
Experiment(s):EBI-1138903 | ||
|
Protein |
nfrA |
Experiment(s):EBI-1138903 | ||
|
Protein |
tdcC |
LCMS(ID Probability):99.0 | ||
|
Protein |
yffB |
LCMS(ID Probability):99.0 | ||
| edit table |
Notes
Mfd is involved in transcription-coupled repair[6][10]. Mfd is is an ATPase that can release stalled or paused RNA polymerases from DNA lesions, including thymine dimers and abasic sites[11]
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MPEQYRYTLP VKAGEQRLLG ELTGAACATL VAEIAERHAG PVVLIAPDMQ NALRLHDEIS QFTDQMVMNL ADWETLPYDS FSPHQDIISS RLSTLYQLPT MQRGVLIVPV NTLMQRVCPH SFLHGHALVM KKGQRLSRDA LRTQLDSAGY RHVDQVMEHG EYATRGALLD LFPMGSELPY RLDFFDDEID SLRVFDVDSQ RTLEEVEAIN LLPAHEFPTD KAAIELFRSQ WRDTFEVKRD PEHIYQQVSK GTLPAGIEYW QPLFFSEPLP PLFSYFPANT LLVNTGDLET SAERFQADTL ARFENRGVDP MRPLLPPQSL WLRVDELFSE LKNWPRVQLK TEHLPTKAAN ANLGFQKLPD LAVQAQQKAP LDALRKFLET FDGPVVFSVE SEGRREALGE LLARIKIAPQ RIMRLDEASD RGRYLMIGAA EHGFVDTVRN LALICESDLL GERVARRRQD SRRTINPDTL IRNLAELHIG QPVVHLEHGV GRYAGMTTLE AGGITGEYLM LTYANDAKLY VPVSSLHLIS RYAGGAEENA PLHKLGGDAW SRARQKAAEK VRDVAAELLD IYAQRAAKEG FAFKHDREQY QLFCDSFPFE TTPDQAQAIN AVLSDMCQPL AMDRLVCGDV GFGKTEVAMR AAFLAVDNHK QVAVLVPTTL LAQQHYDNFR DRFANWPVRI EMISRFRSAK EQTQILAEVA EGKIDILIGT HKLLQSDVKF KDLGLLIVDE EHRFGVRHKE RIKAMRANVD ILTLTATPIP RTLNMAMSGM RDLSIIATPP ARRLAVKTFV REYDSMVVRE AILREILRGG QVYYLYNDVE NIQKAAERLA ELVPEARIAI GHGQMREREL ERVMNDFHHQ RFNVLVCTTI IETGIDIPTA NTIIIERADH FGLAQLHQLR GRVGRSHHQA YAWLLTPHPK AMTTDAQKRL EAIASLEDLG AGFALATHDL EIRGAGELLG EEQSGSMETI GFSLYMELLE NAVDALKAGR EPSLEDLTSQ QTEVELRMPS LLPDDFIPDV NTRLSFYKRI ASAKTENELE EIKVELIDRF GLLPDPARTL LDIARLRQQA QKLGIRKLEG NEKGGVIEFA EKNHVNPAWL IGLLQKQPQH YRLDGPTRLK FIQDLSERKT RIEWVRQFMR ELEENAIA |
| Length |
1,148 |
| Mol. Wt |
129.985 kDa |
| pI |
6.1 (calculated) |
| Extinction coefficient |
95,230 - 96,105 (calc based on 27 Y, 10 W, and 7 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
|
Structure figures
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Selby, CP et al. (1991) Escherichia coli mfd mutant deficient in "mutation frequency decline" lacks strand-specific repair: in vitro complementation with purified coupling factor. Proc. Natl. Acad. Sci. U.S.A. 88 11574-8 PubMed
- ↑ 6.0 6.1 6.2 6.3 Selby, CP & Sancar, A (1993) Molecular mechanism of transcription-repair coupling. Science 260 53-8 PubMed
- ↑ 7.0 7.1 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 9.0 9.1 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Roberts, J & Park, JS (2004) Mfd, the bacterial transcription repair coupling factor: translocation, repair and termination. Curr. Opin. Microbiol. 7 120-5 PubMed
- ↑ Smith, AJ & Savery, NJ (2008) Effects of the bacterial transcription-repair coupling factor during transcription of DNA containing non-bulky lesions. DNA Repair (Amst.) 7 1670-9 PubMed
- ↑ 12.0 12.1 12.2 12.3 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0006281 ! DNA repair
- GO:0006355 ! regulation of transcription, DNA-templated
- GO:0006974 ! cellular response to DNA damage stimulus
- GO:0000716 ! transcription-coupled nucleotide-excision repair, DNA damage recognition
- GO:0000166 ! nucleotide binding
- GO:0003676 ! nucleic acid binding
- GO:0003677 ! DNA binding
- GO:0003684 ! damaged DNA binding
- GO:0003700 ! DNA-binding transcription factor activity
- GO:0004386 ! helicase activity
- GO:0005524 ! ATP binding
- GO:0008026 ! ATP-dependent helicase activity
- GO:0016787 ! hydrolase activity
- Proteins