moaC:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
||
molybdopterin biosynthesis, protein C<ref name='LIB:Riley_2006'/>, B0783<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MoaC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''molybdopterin biosynthesis, protein C<ref name='LIB:Riley_2006'/>, B0783<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MoaC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0772, JW0766, b0783''
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!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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molybdopterin biosynthesis, protein C<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
molybdopterin biosynthesis, protein C<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


MPT synthesis; chlorate resistance protein C<ref name='LIB:EcoGene'/>
|-
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!align=left {{table heading style}} |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
||
||
*


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===Notes===
===Notes===
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{{BacktoTop}}
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<protect>
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<big>'''Gene Ontology'''</big><br />{{Product_GO_help}}<!--box uid=421aa90e079fa326b6494f812ad13e79.21359.J46aa44068199d-->
<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.21359.J46aa44068199d-->
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|
 
|
GO:0006777
|
Mo-molybdopterin cofactor biosynthetic process
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GOA:hamap<br />GO_REF:0000020
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IEA: Inferred from Electronic Annotation
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HAMAP:MF_01224
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-  
|-  
|
|


|
|
[[Category:GO:0005515_!_protein_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0005515_!_protein_binding GO:0005515]
GO:0006777
|
|
protein binding
Mo-molybdopterin cofactor biosynthetic process
|[[PMID:15690043]]<ref name=PMID:15690043/>
|
|
IPI: Inferred from Physical Interaction
GOA:interpro<br />GO_REF:0000002
|
|
[http://www.uniprot.org/uniprot/P0A7L0 UniProtKB:P0A7L0]
IEA: Inferred from Electronic Annotation
|
|
F
InterPro:IPR002820
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
P
|
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
[[Category:GO:0006777_!_Mo-molybdopterin_cofactor_biosynthetic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006777_!_Mo-molybdopterin_cofactor_biosynthetic_process GO:0006777]
GO:0006777
|
|
Mo-molybdopterin cofactor biosynthetic process
Mo-molybdopterin cofactor biosynthetic process
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|
[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000020 GO_REF:0000020]
GOA:spkw<br />SP_KW:GO_REF:0000004
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|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR002820 InterPro:IPR002820]<br />[http://www.uniprot.org/keywords/KW-0501 SP_KW:KW-0501]<br />[http://ca.expasy.org/unirule/MF_01224 HAMAP:MF_01224]
SP_KW:KW-0501
|
|
P
P
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  


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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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Protein
Protein
|
|
[[rplA:Gene_Product(s)|rplA]]<br />
rplA<br />
|
 
|
PMID:15690043
|
Experiment(s):EBI-882449<br />
|-
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Protein
|
djlA<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137964<br />
|-
|
Protein
|
rpmB<br />
|
|


|[[PMID:15690043]]<ref name=PMID:15690043/>
|
|
Experiment(s):[http://www.ebi.ac.uk/iintact/search/do/search?searchString=EBI-882449 EBI-882449]<br />  
PMID:16606699
|
Experiment(s):EBI-1137964<br />
|-  
|
Protein
|
moaB<br />
|


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Experiment(s):EBI-1137964<br />
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Protein
|
rplQ<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137964<br />
|-
|
Protein
|
nadE<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137964<br />
|-
|
Protein
|
rplS<br />
|
 
|
PMID:15690043
|
Experiment(s):EBI-889983<br />
|-
|
Protein
|
rplV<br />
|
 
|
PMID:15690043
|
Experiment(s):EBI-889983<br />
|-
|
Protein
|
rpmB<br />
|
 
|
PMID:15690043
|
Experiment(s):EBI-889983<br />
|-
|
Protein
|
rplS
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
rpmB
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
 
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===Notes===
===Notes===
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!|Compartment!!Description!!Evidence!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
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From EcoCyc<ref name='LIB:EcoCyc11.1'/>   
From EcoCyc<ref name='LIB:EcoCyc11.1'/>  
|
   


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!align=left {{table heading style}} |Name
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AGIQAAKRTW DLIPLCHPLM LSKVEVNLQA EPEHNRVRIE TLCRLTGKTG VEMEALTAAS
AGIQAAKRTW DLIPLCHPLM LSKVEVNLQA EPEHNRVRIE TLCRLTGKTG VEMEALTAAS
VAALTIYDMC KAVQKDMVIG PVRLLAKSGG KSGDFKVEAD D</pre>  
VAALTIYDMC KAVQKDMVIG PVRLLAKSGG KSGDFKVEAD D</pre>  
|-
!align=left {{table heading style}} |Length
||
161
|-
|-
!align=left {{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
||
||
17.47 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
17.466 kDa
|-
|-
!align=left {{table heading style}} |pI
!align=left {{table heading style}} |pI
||
||
7.1 (calculated)
|-
|-
!align=left {{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
||
||
6990 - 7365 (calc based on 1 Y, 1 W, and 3 C residues)  
6,990 - 7,365 (calc based on 1 Y, 1 W, and 3 C residues)


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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
 
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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table>
<tr align="left" valign="top">
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!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
|-
|
Initiator Methionine
|
1
|
Removed
|
[http://www.uniprot.org/uniprot/P0A738#section_features UniProt:P0A738]
|
|-
|
Domain
|
15..150
|
[http://pfam.janelia.org/family/PF01967 PF01967  MoaC family]
|
 
|
PMID:19920124


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<td>
<!-- motifs column 2-->
<motif_map/>
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<span id="Structure"></span><big>'''Structure'''</big>
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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|-
|-
!align=left {{table heading style}} |Structures
!align=left {{table heading style}} |Structures
||
||
<beststructure>moaC
<beststructure>
562</beststructure>
gene=moaC
 
taxon=562,83333
</beststructure>
|-
|-
!align=left {{table heading style}} |Models
!align=left {{table heading style}} |Models
||
||
View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=moaC&sub=keywordSearc EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P0A738 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=moaC&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0A738 PSI-PRED (P0A738)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0A738 Genomes TO Protein (P0A738)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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<!--Structure_notes--></protect>
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==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


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===Notes===
===Notes===
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*  
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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11666-MONOMER EcoCyc:EG11666-MONOMER]
[http://www.ncbi.nlm.nih.gov/protein/16128751 GI:16128751]
|
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_415304.1 GeneID:945397]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0002673
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
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[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
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[http://www.uniprot.org/uniprot/P0A738 UniProtKB/Swiss-Prot:P0A738]
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Escherichia coli str. K-12 substr. MG1655
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[[EcoCyc]]
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EcoCyc:EG11666
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[EcoGene]]
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[[uniprot:P0A738|UniProt:P0A738]]
EcoGene:EG11666
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
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[http://pfam.sanger.ac.uk/family?acc=PF01967 PFAM:PF01967]
[http://www.ncbi.nlm.nih.gov/gene?term=945397 GeneID:945397]
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Escherichia coli str. K-12 substr. MG1655
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[RegulonDB]]
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[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415304 RefSeq:NP_415304]
RegulonDB:ECK120001609
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]])
[[EchoBASE]]
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[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EKR PDB:1EKR]
EchoBASE:EB1617
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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===Categories===
===Categories===
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[[Category:Proteins]]
[[Category:Proteins]]
[[Category:GO:0006777_!_Mo-molybdopterin cofactor biosynthetic process]][[Category:Location:cytoplasm]][[Category:Products with structures in PDB]]

Latest revision as of 20:30, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MoaC

Synonyms

molybdopterin biosynthesis, protein C[1], B0783[2][1], MoaC[2][1] , ECK0772, JW0766, b0783

Product description

molybdopterin biosynthesis, protein C[2][3]

MPT synthesis; chlorate resistance protein C[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01224

P

Seeded from EcoCyc (v14.0)

complete

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002820

P

Seeded from EcoCyc (v14.0)

complete

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0501

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rplA

PMID:15690043[5]

Experiment(s):EBI-882449

Protein

djlA

PMID:16606699[6]

Experiment(s):EBI-1137964

Protein

rpmB

PMID:16606699[6]

Experiment(s):EBI-1137964

Protein

moaB

PMID:16606699[6]

Experiment(s):EBI-1137964

Protein

rplQ

PMID:16606699[6]

Experiment(s):EBI-1137964

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1137964

Protein

rplS

PMID:15690043[5]

Experiment(s):EBI-889983

Protein

rplV

PMID:15690043[5]

Experiment(s):EBI-889983

Protein

rpmB

PMID:15690043[5]

Experiment(s):EBI-889983

Protein

rplS

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpmB

PMID:19402753[7]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm

From EcoCyc[3]


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MSQLTHINAA GEAHMVDVSA KAETVREARA EAFVTMRSET LAMIIDGRHH KGDVFATARI
AGIQAAKRTW DLIPLCHPLM LSKVEVNLQA EPEHNRVRIE TLCRLTGKTG VEMEALTAAS
VAALTIYDMC KAVQKDMVIG PVRLLAKSGG KSGDFKVEAD D
Length

161

Mol. Wt

17.466 kDa

pI

7.1 (calculated)

Extinction coefficient

6,990 - 7,365 (calc based on 1 Y, 1 W, and 3 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P0A738

Domain

15..150

PF01967 MoaC family

PMID:19920124[8]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=moaC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128751

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945397

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002673

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A738

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11666

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11666

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945397

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001609

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1617

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.0 7.1 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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