acrA:Quickview: Difference between revisions
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{{Tab On|Quickview|acrA}}{{Tab|Gene|acrA}}{{Tab|Gene Product(s)|acrA}}{{Tab|Expression|acrA}}{{Tab|Evolution|acrA}}{{Tab|On One Page|acrA}}{{TabsBottom}} | {{Tab On|Quickview|acrA}}{{Tab|Gene|acrA}}{{Tab|Gene Product(s)|acrA}}{{Tab|Expression|acrA}}{{Tab|Evolution|acrA}}{{Tab|On One Page|acrA}}{{TabsBottom}} | ||
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!{{table_heading_style}} | | !align=left {{table_heading_style}} |Standard Name | ||
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''acrA'' | |||
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!{{table_heading_style}} | | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK0457, b0463, JW0452, Mb, lir, mbl, mtcA, sipB, nbsA''<ref name='LIB:Riley_2006'/> | |||
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!{{table_heading_style}} | | !align=left {{table_heading_style}} |Product Desc. | ||
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AcrA Membrane Fusion Protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | AcrA Membrane Fusion Protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ||
Component of [[:Category:Complex:AcrAB-TolC Multidrug Efflux System|AcrAB-TolC Multidrug Efflux System]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:AcrAB-TolC Multidrug Efflux System|AcrAB-TolC Multidrug Efflux Transport System]]<ref name='LIB:EcoCyc11.1'/> | |||
AcrAB-TolC multidrug efflux pump; additionally dye, detergent, solvent resistance; membrane-fusion lipoprotein<ref name='LIB:EcoGene'/> | |||
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!align=left {{table_heading_style}} |Product Synonyms(s) | |||
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''multidrug efflux system<ref name='LIB:Riley_2006'/>, B0463<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SipB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mbl<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Lir<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NbsA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MtcA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AcrA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, acridine efflux pump<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0457, JW0452, lir, Mb, mbl, mtcA, sipB, b0463'' | |||
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!align=left {{table_heading_style}} |Function from GO | |||
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<GO_nr /> | |||
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!{{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!{{table_heading_style}} |Regulation/Expression | !align=left {{table_heading_style}} |Regulation/Expression | ||
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transcription unit(s): [[:Category: | transcription unit(s): [[:Category:Txn_unit:acrAB|acrAB]]<ref name='LIB:EcoCyc10.6'/> | ||
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!{{table_heading_style}} |Regulation/Activity | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=acrA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11703]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001646&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=acrA&loc=MG1655%3A484843..483650,W3110%3A484843..483650,DH10B%3A424174..422981,REL606%3A457686..456493,BW2952%3A386409..387602]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=386409&end=387602&gene=acrA&aa=mnknrgftplavvlmlsgslaltgcddkqaqqggqqmpavgvvtvkteplqittelpgrtsayriaevrpqvsgiilkrnfkegsdieagvslyqidpatyqatydsakgdlakaqaaaniaqltvnryqkllgtqyiskqeydqaladaqqanaavtaakaavetarinlaytkvtspisgrigksnvtegalvqngqatalatvqqldpiyvdvtqssndflrlkqelangtlkqengkakvslitsdgikfpqdgtlefsdvtvdqttgsitlraifpnpdhtllpgmfvrarleeglnpnailvpqqgvtrtprgdatvlvvgaddkvetrpivasqaigdkwlvteglkagdrvvisglqkvrpgvqvkaqevtadnnqqaasgaqpeqsks]] [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=acrA+AND+escherichia+coli]] [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=acrA]] | |||
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==Notes== | ===Notes=== | ||
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acrA was first identified as an acridine sensitive mutation. acrA is a mutational suppressor of topA deletion inviability in low osmolarity medium. AcrA is attached to the inner membrane. acrA is an acrE paralog. AcrA is trimeric. Mar regulon. First 24 aa are a type II signal peptide.<ref name='LIB:EcoGene'/> | |||
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==References== | ==References== | ||
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Latest revision as of 21:53, 27 May 2013
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
acrA |
|---|---|
| Gene Synonym(s) |
ECK0457, b0463, JW0452, Mb, lir, mbl, mtcA, sipB, nbsA[1] |
| Product Desc. |
AcrA Membrane Fusion Protein[2][3]; Component of AcrAB-TolC Multidrug Efflux System[2]; AcrAB-TolC Multidrug Efflux Transport System[3] AcrAB-TolC multidrug efflux pump; additionally dye, detergent, solvent resistance; membrane-fusion lipoprotein[4] |
| Product Synonyms(s) |
multidrug efflux system[1], B0463[2][1], SipB[2][1], Mbl[2][1], Lir[2][1], NbsA[2][1], MtcA[2][1], AcrA[2][1], acridine efflux pump[2][1] , ECK0457, JW0452, lir, Mb, mbl, mtcA, sipB, b0463 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
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Notes
acrA was first identified as an acridine sensitive mutation. acrA is a mutational suppressor of topA deletion inviability in low osmolarity medium. AcrA is attached to the inner membrane. acrA is an acrE paralog. AcrA is trimeric. Mar regulon. First 24 aa are a type II signal peptide.[4]
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.


