fadR:Quickview: Difference between revisions

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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[fadR:Gene|''fadR]]'' (synonyms: ''ECK1175, b1187, JW1176, dec, ole, thdB, oleR'')<ref name='LIB:Riley_2006'/>
''fadR''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[fadR:Gene_Product(s)|FadR product]]<ref name='LIB:Riley_2006'/>: DNA-binding transcriptional dual regulator of fatty acid metabolism product, B1187 product, Ole product, Dec product, ThdB product, OleR product, negative regulator for fad regulon, and positive activator of fabA product
''ECK1175, b1187, JW1176, dec, ole, thdB, oleR''<ref name='LIB:Riley_2006'/>, oleR''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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FadR transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
FadR transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Repressor/activator for fatty acid metabolism regulon; fatty acid-responsive transcription factor; fabAB, iclR activator (regulates aceBAK, glyoxylate shunt); fad repressor; homodimeric<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''DNA-binding transcriptional dual regulator of fatty acid metabolism<ref name='LIB:Riley_2006'/>, B1187<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ole<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Dec<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ThdB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, OleR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FadR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, negative regulator for fad regulon, and positive activator of fabA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , dec, ECK1175, JW1176, ole, oleR, thdB, b1187''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:fadR|fadR]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:fadR|fadR]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=fadR&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10281]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000275&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=fadR&loc=MG1655%3A1234161..1234880,W3110%3A1236515..1237234,DH10B%3A1274402..1275121,REL606%3A1235088..1235807,BW2952%3A1122882..1123601]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1122882&end=1123601&gene=fadR&aa=mvikaqspagfaeeyiiesiwnnrfppgtilpaerelseligvtrttlrevlqrlardgwltiqhgkptkvnnfwetsglniletlarldhesvpqlidnllsvrtnistifirtafrqhpdkaqevlatanevadhadafaeldynifrglafasgnpiyglilngmkglytrigrhyfanpearslalgfyhklsalcsegahdqvyetvrryghesgeiwhrmqknlpgdlaiqgr]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=fadR+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=fadR]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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The fad genes are induced and fabAB, iclR are repressed by long chain acyl-CoA thioesters binding to and releasing FadR from the DNA. FadR is a GntR-type DNA-binding transcriptional regulator.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:51, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

fadR

Gene Synonym(s)

ECK1175, b1187, JW1176, dec, ole, thdB, oleR[1], oleR

Product Desc.

FadR transcriptional dual regulator[2][3]

Repressor/activator for fatty acid metabolism regulon; fatty acid-responsive transcription factor; fabAB, iclR activator (regulates aceBAK, glyoxylate shunt); fad repressor; homodimeric[4]

Product Synonyms(s)

DNA-binding transcriptional dual regulator of fatty acid metabolism[1], B1187[2][1], Ole[2][1], Dec[2][1], ThdB[2][1], OleR[2][1], FadR[2][1], negative regulator for fad regulon, and positive activator of fabA[2][1] , dec, ECK1175, JW1176, ole, oleR, thdB, b1187

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): fadR[2]

Regulation/Activity
Quick Links



        

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Notes

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The fad genes are induced and fabAB, iclR are repressed by long chain acyl-CoA thioesters binding to and releasing FadR from the DNA. FadR is a GntR-type DNA-binding transcriptional regulator.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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