mcbR:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

YncC

Synonyms

predicted DNA-binding transcriptional regulator[1], B1450[2][1], YncC[2][1] , ECK1444, JW1445, yncC, b1450

Product description

predicted DNA-binding transcriptional regulator[2][3]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki. See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000524

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:18309357[4]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0005515

protein binding

PMID:15690043[5]

IPI: Inferred from Physical Interaction

UniProtKB:P60438

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000524

C

Seeded from EcoCyc (v14.0)

complete

GO:0016566

specific transcriptional repressor activity

PMID:18309357[4]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0032582

negative regulation of gene-specific transcription

PMID:18309357[4]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rplC

PMID:15690043[5]

Experiment(s):EBI-880850

Protein

ydbH

PMID:16606699[6]

Experiment(s):EBI-1139864

Protein

lacZ

PMID:16606699[6]

Experiment(s):EBI-1139864

Protein

stfR

PMID:16606699[6]

Experiment(s):EBI-1139864

Protein

rrmA

PMID:16606699[6]

Experiment(s):EBI-1139864

Protein

hchA

PMID:16606699[6]

Experiment(s):EBI-1139864
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MNSFCHAGRV GQKTREGIKM PGTGKMKHVS LTLQVENDLK HQLSIGALKP GARLITKNLA
EQLGMSITPV REALLRLVSV NALSVAPAQA FTVPEVGKRQ LDEINRIRYE LELMAVALAV
ENLTPQDLAE LQELLEKLQQ AQEKGDMEQI INVNRLFRLA IYHRSNMPIL CEMIEQLWVR
MGPGLHYLYE AINPAELREH IENYHLLLAA LKAKDKEGCR HCLAEIMQQN IAILYQQYNR
Length

240

Mol. Wt

27.253 kDa

pI

7.9 (calculated)

Extinction coefficient

15,930 - 16,430 (calc based on 7 Y, 1 W, and 4 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References

Domain

12..74

PF00392 Bacterial regulatory proteins, gntR family

PMID:19920124[7]

Domain

84..210

PF07729 FCD domain

PMID:19920124[7]

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<motif_map/>

Structure
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Structures

<beststructure> gene=mcbR taxon=562,83333 </beststructure>

Models

View models at:

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</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111276

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946014

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0004837

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P76114

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6761

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13773

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946014

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003350

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3535

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 Zhang, XS et al. (2008) Escherichia coli transcription factor YncC (McbR) regulates colanic acid and biofilm formation by repressing expression of periplasmic protein YbiM (McbA). ISME J 2 615-31 PubMed
  5. ↑ 5.0 5.1 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.0 7.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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