yefM:Quickview

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Standard Name

yefM

Gene Synonym(s)

ECK2012, b2017, JW5835[1], JW5835

Product Desc.

antitoxin of the YoeB-YefM toxin-antitoxin pair[2][3];

Component of YoeB-YefM toxin-antitoxin complex[3]

Antitoxin for YoeB toxin; binds YoeB RNase-like domain[4]

Product Synonyms(s)

antitoxin of the YoeB-YefM toxin-antitoxin system[1], B2017[2][1], YefM[2][1] , ECK2012, JW5835, b2017

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yoeB[2]

Regulation/Activity
Quick Links

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Notes

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Homologous to phage P1 Phd antitoxin and Enterococcus faecium antitoxin, Axe. Induced during biofilm formation. yefM-yoeB is the only toxin-antitoxin pair involved in Lon dependent lethality.[4]



References

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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.