maeA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
maeA |
|---|---|
| Gene Synonym(s) | |
| Product Desc. |
MaeA[3]; malate dehydrogenase, NAD-requiring[2]; Component of malic enzyme, NAD-linked[3]; malate dehydrogenase, NAD-requiring[2] Malic enzyme, NAD-dependent; NAD-ME[4] |
| Product Synonyms(s) |
malate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme)[1], B1479[3][1], MaeA[3][1], SfcA[3][1] , ECK1473, JW5238, sfcA, b1479 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
MaeA catalyzes four reactions: I, NAD-dependent L-malate decarboxylation; II, NAD-independent oxalacetate decarboxylation; III, oxalacetate reductase, NAD-dependent; !V, pyruvate reductase, NAD-dependent. Acetyl-CoA and ATP are allosteric inhibitors; aspartate is an allosteric activator. Reaction I proceeds by two steps: dehydrogenation, then decarboxylation.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
