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References Suggestions


Standard Name


Gene Synonym(s)

ECK0026, b0025, JW0023, yaaC[1], yaaC

Product Desc.

RIBF[2]; bifunctional riboflavin kinase / FMN adenylyltransferase[3]

Riboflavin kinase and FAD synthase, riboflavin biosynthesis[4]

Product Synonyms(s)

bifunctional riboflavin kinase and FAD synthetase[1], B0025[2][1], YaaC[2][1], RibF[2][1] , ECK0026, JW0023, yaaC, b0025

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): ribF-ileS-lspA-fkpB-ispH[2], ileS-lsp, ileS-lspA-lytB, ribF-ileS-lspA-slpA-lytB

Quick Links

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The riboflavin kinase is the N-terminal domain; the FAD synthase is the C-terminal domain. RibF is homologous to and can substitute for the essential B. subtilis RibC. ribF is a non-essential gene. Also known as protein X. Biochemical characterization described in Kitatsuji, K., S. Ishino, S. Teshiba, and M. Arimoto, 1993, Process for producing flavine nucleotides, European patent application: 0 542 240 A2.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.