relA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
relA |
|---|---|
| Gene Synonym(s) |
ECK2778, b2784, JW2755, RC[1], RC |
| Product Desc. |
ATP:GTP 3'-pyrophosphotransferase, ppGpp synthetase I; required for ppGpp synthesis during stringent response to amino acid starvation; self regulated[4] |
| Product Synonyms(s) |
(p)ppGpp synthetase I/GTP pyrophosphokinase[1], B2784[2][1], RelA[2][1], ppGpp synthase I[2][1] , ECK2778, JW2755, RC, b2784 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): relA-mazEF[2][3], relA-chpRA, chpA |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
RelA has two physically and functionally distinct domains, the N-terminal domain, amino acids 1 to 455, is responsible for (p)ppGpp synthesis, and the C-terminal domain, amino acids 456 to 744, is responsible for self regulation.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
