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References Suggestions


Standard Name


Gene Synonym(s)

ECK2886, b2891, JW5847, supK[1], supK

Product Desc.

peptide chain release factor RF2[2][3]

Peptide chain release factor 2, RF-2; translation termination factor recognizes UGA and UAA.[4]

Product Synonyms(s)

peptide chain release factor RF-2[1], B2891[2][1], SupK[2][1], PrfB[2][1] , ECK2886, JW5847, supK, b2891

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): dsbC-recJ-prfB[2], prfB-lysS[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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The ribosome changes reading frame after codon 25. The very poor growth of rluD mutants can be suppressed by a point mutation in prfB and a role in translation termination for the 23S rRNA helix 69 pseudouridines has been demonstrated (Ejby, 2007).[4]

prfB in E. coli K-12 has a variation relative other bacteria including E. coli B


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.