ompA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
ompA |
|---|---|
| Gene Synonym(s) |
ECK0948, b0957, JW0940, con, tolG, tut[1], tut |
| Product Desc. |
outer membrane protein 3a (II*;G;d)[2][3] Outer membrane protein A; Outer membrane porin A; T-even phage receptor; weak porin; homodimer, abundant cell surface protein[4] Discovered to influence biofilm formation[5] OmpA inhibits cellulose production through the CpxRA stress response system, and this reduction in cellulose increases biofilm formation on hydrophobic surfaces[6]. Deletion of ompA increases cellulose which decreases biofilm formation on hydrophobic surfaces[6]. |
| Product Synonyms(s) |
outer membrane protein A (3a;II*;G;d)[1], B0957[2][1], Tut[2][1], Con[2][1], TolG[2][1], OmpA[2][1], con, ECK0948, JW0940, tolG, tut, b0957 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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Notes
OmpA is required for colicins K and L and the stabilization of mating aggregates. OmpA is elevated 5X during growth at 4C (enabled by Oleispira antarctica Cpn10/60 transgene). OmpA expression is elevated during biofilm formation (Orme, 2006). OmpA is required for biofilm formation under some condtions. Translation of OmpF is inhibited by the rseX sRNA. Alkali-inducible Binds TrxA (Kumar, 2004). Perhaps because it is so abundant, OmpA is found in some inner membrane preparations.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Barrios, AF et al. (2006) Hha, YbaJ, and OmpA regulate Escherichia coli K12 biofilm formation and conjugation plasmids abolish motility. Biotechnol. Bioeng. 93 188-200 PubMed
- ↑ 6.0 6.1 Ma, Q & Wood, TK (2009) OmpA influences Escherichia coli biofilm formation by repressing cellulose production through the CpxRA two-component system. Environ. Microbiol. 11 2735-46 PubMed
