mak:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
mak |
|---|---|
| Gene Synonym(s) |
ECK0389, b0394, JW0385, yajF[1], yajF |
| Product Desc. |
Cryptic manno(fructo)kinase[4] |
| Product Synonyms(s) |
manno(fructo)kinase[1], B0394[2][1], Mak[2][1], YajF[2][1] , ECK0389, JW0385, yajF, b0394 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
Mak also has low level glucokinase activity; fructose is a much substrate than glucose in vitro. The same (probable) promoter-up mutation was isolated as rescuing both fructose (Sproul, 2001) and glucose kinase (Miller, 2005) deficiences. The original interpretation of the mak-up mutation as in the mak coding region has been clarified by identifying the GTG initiation codon at the previous codon 47, placing the mak-up mutation in the putative promoter region. The unpublished protein sequencing is noted in Miller (2005) and the actual protein sequence data obtained (MRIGIDLGGTKTEVIALGDAGEQLY) was provided as a personal communication to EcoGene from Brian Miller (March, 2006).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
