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References Suggestions


Standard Name


Gene Synonym(s)

ECK1039, b1054, JW1041, htrB, waaM[1], waaM

Product Desc.

Lipid A biosynthesis, KDO2-lipid IVA lauroyl-ACP acyltransferase; not under heat shock regulation; membrane protein affecting cell division, growth, and high-temperature survival[2]

Product Synonyms(s)

lauryl-acyl carrier protein (ACP)-dependent acyltransferase[1], B1054[3][1], WaaM[3][1], HtrB[3][1], LpxL[3][1] , ECK1039, htrB, JW1041, waaM, b1054

Function from GO

<GO_nr />

Knock-Out Phenotype

Does not affect growth at low temperatures but causes a loss of viability at high temperatures in rich media (see PMID:1358874[4])


transcription unit(s): lpxL[3]

Quick Links

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. Karow, M et al. (1992) The lethal phenotype caused by null mutations in the Escherichia coli htrB gene is suppressed by mutations in the accBC operon, encoding two subunits of acetyl coenzyme A carboxylase. J. Bacteriol. 174 7407-18 PubMed