lexA:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
References | Suggestions |
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Standard Name |
lexA |
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Gene Synonym(s) |
ECK4035, b4043, JW4003, exrA, tsl, umuA[1], spr, umuA |
Product Desc. |
Component of LexA transcriptional repressor[2][3] Global regulator (repressor) for SOS regulon; dimeric[4] |
Product Synonyms(s) |
DNA-binding transcriptional repressor of SOS regulon[1], B4043[2][1], Tsl[2][1], UmuA[2][1], ExrA[2][1], LexA[2][1] , ECK4035, exrA, JW4003, spr, tsl, umuA, b4043 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression | |
Regulation/Activity | |
Quick Links | |
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Notes
LexA autocleavage, stimulated by RecA, of the first 84 aa of LexA removes the DNA binding region and is required to activate the SOS response. LexA recognition site: CTGTATATATATACAG.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.