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References Suggestions


Standard Name


Gene Synonym(s)

ECK0085, b0084, JW0082, pbpB, sep[1], sep

Product Desc.

essential cell division protein FtsI; penicillin-binding protein 3[2][3]

Transpetidase, PBP3; penicillin-binding protein 3 involved in septal peptidoglycan synthesis[4]

Product Synonyms(s)

transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3)[1], B0084[2][1], Sep[2][1], PbpB[2][1], FtsI[2][1], PBP3[2][1] , ECK0085, JW0082, pbpB, sep, b0084

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): mraZW-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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FtsI is recruited by its cognate SEDS protein FtsW. Essential gene, Hara (1997). FtsI was reported to be a lipoprotein (Hayashi, 1989), but only 15% of the protein was modified. The physiological significance of this is unknown. The sequence is not predicted to be a lipoprotein cleavage site. Divisome.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.