dtpA:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
References | Suggestions |
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Standard Name |
dtpA |
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Gene Synonym(s) | |
Product Desc. |
YdgR putative peptide POT Transporter[2][3] Tripeptide and dipeptide permease[4] |
Product Synonyms(s) |
predicted transporter[1], B1634[2][1], YdgR[2][1], DtpA[2][1] , ECK1630, JW1626, tppB, ydgR, b1634 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression | |
Regulation/Activity | |
Quick Links | |
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Notes
Overexpression increases di- and tri-peptide transport and confers hypersensitivity to alafosfalin (Weitz, 2006). TppB was originally characterized in S. typhimurium. OmpR regulon. tppB is weakly stimulated by anaerobiosis in E. coli; Salmonella tppB is strongly stimulated by anaerobiosis. tppB in both species is not regulated by osmolarity. Salmonella tppA regulatory mutations were shown to be ompR mutations. Salmonella tppB mutants are resistant to the tripeptide antibiotic alafosfalin and cannot satisfy a leucine requirement with trileucine (Gibson, 1984). Major Facilitator Superfamily (MFS).[4]
References
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- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.