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References Suggestions


Standard Name


Gene Synonym(s)

ECK2691, b2696, JW2666, zfiA[1], zfiA

Product Desc.

carbon storage regulator; controls glycogen synthesis, gluconeogenesis, cell size and surface properties[2][3];

Component of CsrA complex with CsrB RNA[3]

Global regulator of carbon source metabolism; CsrA exerts reciprocal effects on glycolysis versus gluconeogenesis and glycogen biosynthesis; glgC mRNA-binding activity blocks GlgC translation; csrB RNA inhibits csrA[4]

Product Synonyms(s)

pleiotropic regulatory protein for carbon source metabolism[1], B2696[2][1], ZfiA[2][1], CsrA[2][1] , ECK2691, JW2666, zfiA, b2696

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): csrA[2]

Quick Links

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Recombinant CsrA-His6 was N-terminally sequenced, but this does not Verify since translation start was forced at ATG: Met is not clipped: MLIL start. CsrA also postively regulates FlhCD post-translationally, and hence is required for motility.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.