From EcoliWiki
(Redirected from crl)
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions


Standard Name


Gene Synonym(s)

ECK0241, b0240, JW0230[1], JW0230

Product Desc.

Crl transcriptional regulator[2][3]

Stimulates RNA polymerase holoenzyme formation; stimulates RpoS activity during stationary phase; mutants display rpoS mutant phenocopy; does not reduce amount of RpoS protein[4]

Product Synonyms(s)

DNA-binding transcriptional regulator[1], B0240[2][1], Crl[2][1] , ECK0241, JW0230, b0240

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): crl[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

</protect> See Help:Quickview for help with entering information in the Quickview table. <protect></protect>


[back to top]

RpoD, RpoS and RpoH sigma factor-containing holoenzyme assembly is stimulated by Crl (Gaal, 2006). Accumulation of Crl during stationary phase at 30C, but not 37C, suggests it is a thermosensor controlling sigma(S) activity. Initially identified due to reduction of RpoS-dependent curlin (csgAB) expression.[4]


[back to top]

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.