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References Suggestions


Standard Name


Gene Synonym(s)

ECK2213, b2220, JW2214, Az[1], Az

Product Desc.

Response regulator for atoDAEB operon[2]

Response regulator for atoDAEB operon; AtoS is the two-component cognate sensor protein; induced by acetoacetate; ornithine decarboxylase antizyme Az, polyamine-inducible[3]

Product Synonyms(s)

B2220[4][1], Az, ECK2213, JW2214, b2220

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): atoS[4]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Bifunctional bacterial antizyme AtoC(Az) binds to and inhibits ornithine decarboxylase. AtoCS mutants have lowered complexed poly-(R)-3-hydroxybutyrate (cPHB) levels: the ato operon is required for maximal cPHB production (Theodoroua, 2006).[3]


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  1. 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 3.0 3.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. 4.0 4.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7