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References Suggestions


Standard Name


Gene Synonym(s)

ECK2018, b2023, JW2005[1], JW2005

Product Desc.

imidazole glycerol phosphate synthase, HisH subunit[2][3];

Component of imidazole glycerol phosphate synthase[2][3]

Amidotransferase component of imidazole glycerol phosphate (IGP) synthase[4]

Product Synonyms(s)

imidazole glycerol phosphate synthase, glutamine amidotransferase subunit with HisF[1], B2023[2][1], HisH[2][1], hisH enzyme[2][1] , ECK2018, JW2005, b2023

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): hisBHAFI[2], hisLGDCBHAFI[2]

Quick Links

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N-terminus of purified HisH was sequenced by Klem and Davisson (1993), and the fMet is not clipped. Omitted from Verified set because natural RBS was not used. Natural RBS is very good and this is almost certainly the in vivo start[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.