dtpA:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
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Standard Name

dtpA

Gene Synonym(s)

ydgR, ECK1630, b1634, JW1626, tppB[1][2], JW1626, tppB

Product Desc.

YdgR putative peptide POT Transporter[2][3]

Tripeptide and dipeptide permease[4]

Product Synonyms(s)

predicted transporter[1], B1634[2][1], YdgR[2][1], DtpA[2][1] , ECK1630, JW1626, tppB, ydgR, b1634

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): dtpA[2], ydgR

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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Overexpression increases di- and tri-peptide transport and confers hypersensitivity to alafosfalin (Weitz, 2006). TppB was originally characterized in S. typhimurium. OmpR regulon. tppB is weakly stimulated by anaerobiosis in E. coli; Salmonella tppB is strongly stimulated by anaerobiosis. tppB in both species is not regulated by osmolarity. Salmonella tppA regulatory mutations were shown to be ompR mutations. Salmonella tppB mutants are resistant to the tripeptide antibiotic alafosfalin and cannot satisfy a leucine requirement with trileucine (Gibson, 1984). Major Facilitator Superfamily (MFS).[4]



References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.