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References Suggestions


Standard Name


Gene Synonym(s)

ECK0516, b0523, JW0512, Pur2, ade3, adef, ade(f)[1], ade

Product Desc.


Component of N5-carboxyaminoimidazole ribonucleotide mutase[2][3]

N5-carboxyaminoimidazole ribonucleotide (N-CAIR) mutase; purine synthesis[4]

Product Synonyms(s)

N5-carboxyaminoimidazole ribonucleotide mutase[1], B0523[2][1], PurE[2][1], purE1 peptide[2][1], catalytic subunit[2][1], N5-CAIR mutase[2][1], AIR carboxylase subunit[2][1], N5-carboxyaminoimidazole ribonucleotide mutase subunit[2][1] , ade, ade3, ECK0516, JW0512, Pur2, b0523

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): purEK[2], OP00112, purE

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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PurE was previously thought to be the catalytic subunit of phosphoribosylaminoimidazole carboxylase, with ATPase subunit PurK (Tiedeman, 1989). PurE is a separate N-CAIR mutase (Mueller, 1994; Meyer, 1999).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.