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References Suggestions


Standard Name


Gene Synonym(s)

ECK0020, b0019, JW0018, ant, antA, hyc[1]

Product Desc.

sodium/proton NhaA transporter[2][3]

Na+/H+ antiporter 1, strongly pH-dependent; helps regulate intracellular pH and extrude lithium; nhaA_P1 activated by NhaR, repressed by H-NS and stimulated by Na(+)[4]

Product Synonyms(s)

sodium-proton antiporter[1], B0019[2][1], Hyc[2][1], Ant[2][1], AntA[2][1], NhaA[2][1] , ant, antA, ECK0020, JW0018, b0019

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): nhaA[2], OP00281

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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nhaA P2 promoter is RpoS-regulated, but H-NS, Na(+)- and NhaR-independent.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.