EcoliWiki:PanGenome

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Definition

Possible definitions include:

  • Any gene in any E. coli strain.
  • This comes close:

    A decade after the beginning of the genomic era, the question of how genomics can describe a bacterial species has not been fully addressed. Experimental data have shown that in some species new genes are discovered even after sequencing the genomes of several strains. Mathematical modeling predicts that new genes will be discovered even after sequencing hundreds of genomes per species. Therefore, a bacterial species can be described by its pan-genome, which is composed of a "core genome" containing genes present in all strains, and a "dispensable genome" containing genes present in two or more strains and genes unique to single strains. Given that the number of unique genes is vast, the pan-genome of a bacterial species might be orders of magnitude larger than any single genome.[1]


Policy Regarding ...

What EcoliWiki contains

  • EcoliWiki contains[2] the pangenome consisting of the non-enteropathogenic strains of E. coli.
  • A list of currently available strains can be found here.
  • MG1655 and W3110 were designated the reference strains.




References

See Help:References for how to manage references in EcoliWiki.

  1. Medini, D et al. (2005) The microbial pan-genome. Curr. Opin. Genet. Dev. 15 589-94 PubMed
  2. Well, we don't have exactly 100% of the pangenome, but we're working on it. Send us your E. coli info!