Cis Element:Phage lambda ori
Cis element summary table
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Standard Name |
Lambda ori |
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Synonyms | |
Function |
Initiation control site for replication of the lambda genome |
Location |
within O gene |
SO terms |
|
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Notes
Location and Sequence
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Strain | Map location | Genome coordinates | Genome browsers | Sequence links |
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Phage Lambda (NC_001416) |
NC_001416: 39034..39137 |
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Notes
- The lambda ori has 4 repeated segments (commonly referred to as 'iterons') located at the following coordinates[1]:
- ori1 - nt 39034 - 39051
- ori2 - nt 39054 - 39071
- ori3 - nt 39078 - 39095
- ori4 - nt 39101 - 39118
Below is the location of each of the ori iteron (underlined) in the lambda genomic sequence [1] :
Lambda nt39034 ATCCCTCAAA ACGAGGGAAA ATCCCCTAAAA CGAGGGATAA AACATCCCTC AAATTGGGGG ATTGCT 39100
Lambda nt39101 ATCCCTCAAA ACAGGGGGAC ACAAAAGACA CTATTACAAA AGAAAAAAGA AAA 39153
Interactions
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Partner Type | Partner | Notes | References | Evidence |
---|---|---|---|---|
Protein |
Phage lambda O protein |
Purified O protein protects lambda DNA in the ori region from ExoIII nuclease digestion (FIgure 2) and DNase cleavage (Figure 4). | ||
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Notes
Mutant alleles and phenotypes
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Allele | Nt change(s) | Phenotype: Type | Phenotype: Description | Reference | Availability | Comments |
---|---|---|---|---|---|---|
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Notes
Genetic Resources
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Resource | Resource Type | Source | Notes/Reference |
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Notes
Accessions
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Database | Accession | Notes |
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EcoCyc: |
Escherichia coli str. K-12 substr. MG1655 | |
EcoGene: |
Escherichia coli str. K-12 substr. MG1655 | |
RegulonDB: |
Escherichia coli str. K-12 substr. MG1655 | |
EchoBASE: |
Escherichia coli str. K-12 substr. MG1655 | |
ASAP: |
Escherichia coli str. K-12 substr. MG1655 | |
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Notes
References
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- ↑ 1.0 1.1 Moore, DD et al. () Sequence organization of the origins of DNA replication in lambdoid coliphages. Gene 14 91-101 PubMed
- ↑ Tsurimoto, T & Matsubara, K (1981) Purified bacteriophage lambda O protein binds to four repeating sequences at the lambda replication origin. Nucleic Acids Res. 9 1789-99 PubMed