stpA:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

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Standard Name

stpA

Gene Synonym(s)

ECK2663, b2669, JW2644, hnsB, rsv[1]

Product Desc.

H-NS-like DNA-binding protein with RNA chaperone activity[2][3]

RNA chaperone and DNA-binding protein; suppresses T4 td mutant; modulates micF stability; forms heteromers with, and stabilzed against proteolysis by, the paralogous H-NS protein; transcriptionally repressed by H-NS[4]

Product Synonyms(s)

DNA binding protein, nucleoid-associated[1], B2669[2][1], HnsB[2][1], StpA[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): stpA[2]

Regulation/Activity


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Notes

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Nucleoid-associated protein.

StpA binds prefereably unstructured RNA weakly, with mainly electrostatic interactions that promote RNA folding (Mayer, 2007).[4]


References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.