queC:Quickview

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Standard Name

queC

Gene Synonym(s)

ybaX, ECK0438, b0444, JW0434[1][2]

Product Desc.

enzyme in preQ0 biosynthesis [2][3]

Required for 7-cyano-7-deazaguanine (preQ0) synthesis; queuosine biosynthesis, step 1[4]

Product Synonyms(s)

predicted aluminum resistance protein[1], B0444[2][1], YbaX[2][1], QueC[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ybaX[2]

Regulation/Activity


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Notes

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Asn, Asp, Tyr, and His tRNA anticodons are modified. A. viscosus ortholog ALU1 confers aluminum tolerance when cloned in E. coli (Jo, 1997). COG0603 predicts ATPase activity. AFMB Structural Genomics target No. 25 (http://afmb.cnrs-mrs.fr/article171.html). tgt mutants lack queuosine and are have reduced survival in stationary phase. (Noguchi, 1982).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.