folK:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name
Gene Synonym(s)
Product Desc.
Product Synonyms(s)
Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
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See Help:Quickview for help with entering information in the Quickview table.

Notes

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HPPK active center is formed once both substrates, ATP and HP, are bound and this assembly results in confirmational changes primarily in catalytic loops 1-3; catalytic loop 3 moves in the opposite direction upon binding of the nucleotide. Catalytic loop 3 is involved in ternary complex stabilization and is necessary for catalysis.[1]



References

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  1. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.