der:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

der (synonyms: ECK2507, b2511, JW5403, engA, yfgK)[1]

Product(s)

Der product[1]: predicted GTP-binding protein product, B2511 product, YfgK product, EngA product

Description

50S ribosomal subunit stability factor[2][3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yfgL-der[2]

Regulation/Activity


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Notes

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Der-depletion alters ribosome stability and/or biogenesis, as evidenced by polysome profiles (Bharat, 2006). Der has two tandem GTP-binding domains. der is an essential gene.[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.