iscR:Expression

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Overview Transcription Translation Turnover Experimental Links References Suggestions

Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Transcription and Transcriptional Regulation

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Transcription unit(s)

iscRSUA

The transcription unit is likely to be longer and include hscBhscAfdx and possibly yfhJpepBsseB PMID:16677314[1]

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Figure courtesy of RegulonDB

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Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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gbrowse_img.php?coord=2660133..2660173&genome=ecoli&name=MG1655&trackset=Genes_unlabeled+DNA_unlabeled+flip&width=400&.png
This picture shows the sequence around the N-terminus.

Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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Mutations Affecting Expression

Allele Name Mutation Phenotype Reference
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Expression Studies

Type Reference Notes

microarray

EcoliGenExpDB:b2531 (EcoliWiki Page)

Summary of data for iscR from multiple microarray studies

microarray

GEO Profiles:b2531 (EcoliWiki Page)

NCBI GEO profiles for iscR

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Expression Resources

Resource Name Resource Type Description Source Notes

GFP Fusion

Intergenic region (2660080..2660665) fused to gfpmut2.

OpenBioSystems

Raw protomer fusion data from Zaslaver, et al.
Plate:109-AZ10; Well:D9[2]

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Notes

Accessions Related to iscR Expression

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:G7326

EchoBASE (EcoliWiki Page)

EchoBASE:EB3178

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b2531

EcoGene (EcoliWiki Page)

EcoGene:EG13397

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Notes

Links

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Name URL Comments
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References

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  1. ↑ Giel, JL et al. (2006) IscR-dependent gene expression links iron-sulphur cluster assembly to the control of O2-regulated genes in Escherichia coli. Mol. Microbiol. 60 1058-75 PubMed
  2. ↑ Zaslaver, A et al. (2006) A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nat. Methods 3 623-8 PubMed


Categories

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