secM:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

secM

Gene Synonym(s)

ECK0098, b0097, JW5007, srrA, yacA, gene X[1][2]

Product Desc.

secretion monitor that regulates SecA translation (General Secretory Pathway)[2][3]

Secretion monitor controlling secA expression[4]

Product Synonyms(s)

regulator of secA translation[1], B0097[2][1], SrrA[2][1], SecM[2][1], YacA[2][1], Gene X[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): secMA-mutT[2]

Regulation/Activity
Quick Links

PortEco search(secM)    DNA display    Protein display    Pubmed(secM)    Textpresso(secM)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Translation and secretion of SecM regulates downstream secA gene expression. First 37 aa are predicted signal peptide. The arrest sequence is 150-FXXXXWIXXXXGIRAGP-166. The arrested peptide ends with G165: P-166 encodes an arrest requirement for free Pro166-tRNA in the ribosomal peptidyl transferase A site (Muto 2006).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.