secM:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
secM |
|---|---|
| Gene Synonym(s) | |
| Product Desc. |
secretion monitor that regulates SecA translation (General Secretory Pathway)[2][3] Secretion monitor controlling secA expression[4] |
| Product Synonyms(s) |
regulator of secA translation[1], B0097[2][1], SrrA[2][1], SecM[2][1], YacA[2][1], Gene X[2][1] , ECK0098, JW5007, srrA, yacA, b0097 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): secMA-mutT[2] |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
Translation and secretion of SecM regulates downstream secA gene expression. First 37 aa are predicted signal peptide. The arrest sequence is 150-FXXXXWIXXXXGIRAGP-166. The arrested peptide ends with G165: P-166 encodes an arrest requirement for free Pro166-tRNA in the ribosomal peptidyl transferase A site (Muto 2006).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
