plsX:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
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| Standard Name |
plsX |
|---|---|
| Gene Synonym(s) |
ECK1076, b1090, JW5156[1] |
| Product Desc. |
fatty acid/phospholipid synthesis protein[2][3] Probable phosphate:acyl-ACP acyltransferase; confers glycerol phosphate auxotrophy, when combined with a plsB Km missense mutant[4] |
| Product Synonyms(s) |
fatty acid/phospholipid synthesis protein[1], B1090[2][1], PlsX[2][1] |
| Function from GO |
Biological Process
|
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): plsX-fabHDG[2], rpmF-plsX-fabHDG[2] |
| Regulation/Activity | |
| Quick Links | |
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Notes
PlsX is homologous to the S. pneumoniae phosphate:acyl-ACP acyltransferase PlsX (UniProt: Q97TA6) (Lu, 2006). ygiH(plsY) and plsX are synthetic lethals (Yoshimura, 2007). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.