mrcB:Quickview: Difference between revisions

From EcoliWiki
Jump to navigation Jump to search
← Older editNewer edit →
imported>Wikientrybot
No edit summary
Update TableEdit tables.
Line 24: Line 24:
*  
*  
****************************************************************************************** -->{{Quickview_table_help}}
****************************************************************************************** -->{{Quickview_table_help}}
{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  
{| id="G49aeed2dec527" class=" tableEdit New_Quickview_Table"


|-
|-
!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
||
||
''mrcB''  
''mrcB''  
|-
|-
!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
||
||
''ECK0148, b0149, JW0145, pbpF, ponB''<ref name='LIB:Riley_2006'/>
''ECK0148, b0149, JW0145, pbpF, ponB''<ref name='LIB:Riley_2006'/>
|-
|-
!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
||
||
MrcB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
MrcB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
Line 43: Line 43:
Murein polymerase, PBP1B; bifunctional murein transglycosylase and transpeptidase; penicillin-binding protein 1B; dimeric<ref name='LIB:EcoGene'/>
Murein polymerase, PBP1B; bifunctional murein transglycosylase and transpeptidase; penicillin-binding protein 1B; dimeric<ref name='LIB:EcoGene'/>
|-
|-
!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
||
||
fused glycosyl transferase<ref name='LIB:Riley_2006'/>, transpeptidase<ref name='LIB:Riley_2006'/>, B0149<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PonB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PbpF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MrcB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PBP1B<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
fused glycosyl transferase<ref name='LIB:Riley_2006'/>, transpeptidase<ref name='LIB:Riley_2006'/>, B0149<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PonB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PbpF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MrcB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PBP1B<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
|-
|-
!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
||
||


|-
|-
!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
||
||
transcription unit(s): [[:Category:Txn_unit:mrcB|mrcB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:mrcB|mrcB]]<ref name='LIB:EcoCyc10.6'/>  
|-
|-
!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
||
||




|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.2059.G49aeed2dec527&page=2059&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table] ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.2059.G49aeed2dec527&page=2059&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table]</span> ||
|}
|}
<!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.2059.G49aeed2dec527--></protect>
<!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.2059.G49aeed2dec527--></protect>

Revision as of 02:15, 9 January 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

mrcB

Gene Synonym(s)

ECK0148, b0149, JW0145, pbpF, ponB[1]

Product Desc.

MrcB[2][3];

Component of penicillin-binding protein 1B[3]

Murein polymerase, PBP1B; bifunctional murein transglycosylase and transpeptidase; penicillin-binding protein 1B; dimeric[4]

Product Synonyms(s)

fused glycosyl transferase[1], transpeptidase[1], B0149[2][1], PonB[2][1], PbpF[2][1], MrcB[2][1], PBP1B[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mrcB[2]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


MrcB is part of a complex with MltA and MipA. The N-terminal transglycosylase activity polymerizes the glycan backbone and is penicillin-insensitive. The C-terminal transpeptidase activity crosslinks the muramic peptides and is penicillin-sensitive. Full length MrcB is the alpha isoform. A second in vivo ATG start at codon 46 produces the 799 aa gamma isoform. Murein polymerase is an essential function satisfied by either MrcA or MrcB. Mutants have elevated OM vesiculation (McBroom, 2006). MrcB is a membrane-bound periplasmic enzyme that has an uncleaved signal anchor.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=mrcB:Quickview&oldid=982570"