gspB:Quickview: Difference between revisions

From EcoliWiki
Jump to navigation Jump to search
imported>Wikientrybot
No edit summary
imported>Wikientrybot
No edit summary
Line 28: Line 28:
|-
|-
!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
||
''gspB''
|-
|-
!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
||
''pioO, ECK3309, b3322, JW3284, pinO''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc11.1'/>
|-
|-
!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
||
calcium-binding protein required for initiation of chromosome replication<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
Part of H-NS-silenced gsp divergon, type II protein secretion; cloned gsp divergon secretes ChiA, requires gspAB operon<ref name='LIB:EcoGene'/>
|-
|-
!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
||
part of gsp divergon involved in type II protein secretion<ref name='LIB:Riley_2006'/>, B3322<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GspB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PioO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PinO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
|-
!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
||
|-
|-
!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
||
transcription unit(s): [[:Category:Txn_unit:pioO|pioO]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:gspA-pioO|gspA-pioO]]<ref name='LIB:EcoCyc10.6'/>
|-
|-
!align=left {{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
||


|-class='sortbottom'
|-class='sortbottom'
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.8380.J49aee828dcb0a&page=8380&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table]
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.8380.J49aee828dcb0a&page=8380&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table] ||
|}
|}
<!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.8380.J49aee828dcb0a--></protect>
<!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.8380.J49aee828dcb0a--></protect>

Revision as of 20:44, 4 March 2009

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

gspB

Gene Synonym(s)

pioO, ECK3309, b3322, JW3284, pinO[1][2]

Product Desc.

calcium-binding protein required for initiation of chromosome replication[3][2]

Part of H-NS-silenced gsp divergon, type II protein secretion; cloned gsp divergon secretes ChiA, requires gspAB operon[4]

Product Synonyms(s)

part of gsp divergon involved in type II protein secretion[1], B3322[3][1], GspB[3][1], PioO[3][1], PinO[3][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): pioO[3], gspA-pioO[3]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


GspB is a distant homolog or convergent analog of exeB of A. hydrophila, which is required for protein export , specifically for the export and assembly of secretin (ExeD/GspD) into the outer membrane. GspB has a single predicted N-terminal transmembrane segment (28-50), followed by a predicted periplasmic domain, which may interact with GspA. GspA may interact with GspB. A divergon is a regulon comprised of two adjacent divergent operons or genes. gspB was initially identified as an ORF that might be the 11.3 kDa PinO protein synthesized in the absence of isoleucine in relA stains (Guzman, 1991). But GspB is predicted to be 15.9 kDa and has isoleucine residues and there is no evidence that gspB encodes the PinO peptide or that it binds calcium. No homology to calmodulin or other calcium-binding proteins is predicted. gspB may have been mistaken for pinO due to use of a downstream ATG as start codon, but the 11 kD C-terminal fragment does have an Ile reside in it, making gspB inconsistent with pinO. pioO was the prior gene name assigned to pinO since the gene name pin was already taken.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.